Medennium posterior chamber phakic refractive lens to correct high myopia

Celeste Marina Verde, Miguel A Teus, Esther Arranz-Marquez, Raquel Gil Cazorla

Research output: Contribution to journalArticlepeer-review


PURPOSE: To determine the efficacy and safety of phakic refractive lens implantation to correct high myopia.

METHODS: In this prospective study, a phakic refractive lens was implanted in 90 myopic eyes in which refractive errors ranged from -6.00 to -20.00 diopters (D) and laser refractive surgery was contraindicated. Uncorrected visual acuity (UCVA) and best-spectacle corrected visual acuity (BSCVA), manifest and cycloplegic refractions, and intraocular pressure (IOP) were assessed during a 1-year follow-up period. Possible complications, including endothelial cell counts, were evaluated.

RESULTS: Spherical equivalent refraction measurements revealed a significant change from the preoperative mean value of -11.90+/-5.00 D to 0.04+/-0.20 D 1 year postoperatively (P=.001). The UCVA and BSCVA significantly improved postoperatively (P=.001 and P=.01, respectively). Seventy-two (80%) eyes and 61 (68%) eyes were within +/-1.00 D and +/-0.50 D of the target refraction, respectively. A significant increase in IOP was found at every postoperative visit (P=.01). There was a trend toward decreased endothelial cell density postoperatively, although the difference did not reach significance. No major complications were found during the 1-year follow-up period.

CONCLUSIONS: The implantation of a phakic refractive lens seems to be a predictable and well-tolerated procedure for correcting high myopia. Complications such as development of cataract, implant dislocation, decreases in endothelial cell counts, or development of glaucoma did not occur in this study.

Original languageEnglish
Pages (from-to)900-904
Number of pages5
JournalJournal of Refractive Surgery
Issue number9
Publication statusPublished - Nov 2007


  • Adult
  • Cell Count
  • Endothelium, Corneal/pathology
  • Eyeglasses
  • Follow-Up Studies
  • Humans
  • Lens Implantation, Intraocular/adverse effects
  • Myopia/physiopathology
  • Ocular Hypertension/etiology
  • Phakic Intraocular Lenses/adverse effects
  • Postoperative Complications
  • Predictive Value of Tests
  • Prospective Studies
  • Refraction, Ocular
  • Severity of Illness Index
  • Treatment Outcome
  • Visual Acuity


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