Meningeal Lymphatic Pathway of Brain Clearing From the Blood After Haemorrhagic Injuries

O. Semyachkina-glushkovskaya, N. Navolokin, A. Shirokov, A. Terskov, A. Khorovodov, A. Mamedova, M. Klimova, E. Rafailov, J. Kurths

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This seems to be the time to gain new knowledge about the meningeal lymphatic system and a deeper understanding of its anatomy and physiology. Although it is known that the meningeal lymphatics present in the layers of the brain, limited information is available about the role of this system in brain function. Here, for the first time we clearly demonstrate that the meningeal lymphatic pathway is involved in brain clearing from the blood after intracranial hemorrhage associated with hypoxia and forms a connective bridge between interstitial, cerebral spinal fluid and peripheral lymphatics. We also show that the development of methods to stimulate meningeal lymph flow after hemorrhagic evidence in the brain might be a neuroprotective strategy for effective recovery of the brain after a cerebrovascular catastrophe.
Original languageEnglish
Title of host publicationOxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology
EditorsP.D. Ryu, J. LaManna, D. Harrison, S.S. Lee
PublisherSpringer
Pages63-68
Number of pages6
DOIs
Publication statusPublished - 1 Jan 2020

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1232
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Fingerprint

Wounds and Injuries
Brain
Lymphatic System
Intracranial Hemorrhages
Lymph
Anatomy
Hypoxia

Bibliographical note

© Springer Nature Switzerland AG 2020.

Keywords

  • Blood-brain barrier
  • Brain drainage and clearance
  • Hypoxia
  • Intracranial hemorrhages
  • Lymphatic system

Cite this

Semyachkina-glushkovskaya, O., Navolokin, N., Shirokov, A., Terskov, A., Khorovodov, A., Mamedova, A., ... Kurths, J. (2020). Meningeal Lymphatic Pathway of Brain Clearing From the Blood After Haemorrhagic Injuries. In P. D. Ryu, J. LaManna, D. Harrison, & S. S. Lee (Eds.), Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology (pp. 63-68). [Chapter 9] (Advances in Experimental Medicine and Biology; Vol. 1232). Springer. https://doi.org/10.1007/978-3-030-34461-0_9
Semyachkina-glushkovskaya, O. ; Navolokin, N. ; Shirokov, A. ; Terskov, A. ; Khorovodov, A. ; Mamedova, A. ; Klimova, M. ; Rafailov, E. ; Kurths, J. / Meningeal Lymphatic Pathway of Brain Clearing From the Blood After Haemorrhagic Injuries. Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology. editor / P.D. Ryu ; J. LaManna ; D. Harrison ; S.S. Lee. Springer, 2020. pp. 63-68 (Advances in Experimental Medicine and Biology).
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Semyachkina-glushkovskaya, O, Navolokin, N, Shirokov, A, Terskov, A, Khorovodov, A, Mamedova, A, Klimova, M, Rafailov, E & Kurths, J 2020, Meningeal Lymphatic Pathway of Brain Clearing From the Blood After Haemorrhagic Injuries. in PD Ryu, J LaManna, D Harrison & SS Lee (eds), Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology., Chapter 9, Advances in Experimental Medicine and Biology, vol. 1232, Springer, pp. 63-68. https://doi.org/10.1007/978-3-030-34461-0_9

Meningeal Lymphatic Pathway of Brain Clearing From the Blood After Haemorrhagic Injuries. / Semyachkina-glushkovskaya, O.; Navolokin, N.; Shirokov, A.; Terskov, A.; Khorovodov, A.; Mamedova, A.; Klimova, M.; Rafailov, E.; Kurths, J.

Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology. ed. / P.D. Ryu; J. LaManna; D. Harrison; S.S. Lee. Springer, 2020. p. 63-68 Chapter 9 (Advances in Experimental Medicine and Biology; Vol. 1232).

Research output: Chapter in Book/Report/Conference proceedingChapter

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Semyachkina-glushkovskaya O, Navolokin N, Shirokov A, Terskov A, Khorovodov A, Mamedova A et al. Meningeal Lymphatic Pathway of Brain Clearing From the Blood After Haemorrhagic Injuries. In Ryu PD, LaManna J, Harrison D, Lee SS, editors, Oxygen Transport to Tissue XLI. Advances in Experimental Medicine and Biology. Springer. 2020. p. 63-68. Chapter 9. (Advances in Experimental Medicine and Biology). https://doi.org/10.1007/978-3-030-34461-0_9