Modelling a biochemical reaction with computational fluid dynamics

Sotos C. Generalis*, Gregory M. Cartland Glover

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Earlier investigations (Cartland Glover et al., 2004) into the use of computational fluid dynamics (CFD) for the modelling of gas-liquid and gas-liquid-solid flow allowed a simple biochemical reaction model to be implemented. A single plane mesh was used to represent the transport and reaction of molasses, the mould Aspergillus niger and citric acid in a bubble column with a height to diameter aspect ratio of 20:1. Two specific growth rates were used to examine the impact that biomass growth had on the local solids concentration and the effect this had on the local hydrodynamics of the bubble column.

Original languageEnglish
JournalInternational Journal of Chemical Reactor Engineering
Issue numberA50
Publication statusPublished - 2005

Bibliographical note

Berkeley Electronic Press © 2005


  • bubble columns reactors
  • computational fluid dynamics
  • fermentation
  • gas-liquid-solid flows
  • mixture model


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