Molecular pathways leading to cancer cachexia

Michael J. Tisdale

doi:10.1152/physiol.00019.2005

Molecular pathways leading to cancer cachexia

Michael J. Tisdale^*

^*Corresponding author for this work

College of Health and Life Sciences

Research output: Contribution to journal › Article › peer-review

176 Citations (SciVal)

Abstract

Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue. ©2005 Int. Union Physiol. Sci./Am. Physiol. Soc.

Original language	English
Pages (from-to)	340-348
Number of pages	9
Journal	Physiology
Volume	20
Issue number	5
DOIs	https://doi.org/10.1152/physiol.00019.2005
Publication status	Published - Oct 2005

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

body weight
cancer patients
morbidity
mortality
tumor
host factors
tissue catabolism
cachexia
upregulation
skeletal muscle
adipose tissue

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10.1152/physiol.00019.2005

Cite this

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title = "Molecular pathways leading to cancer cachexia",

abstract = "Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue. {\textcopyright}2005 Int. Union Physiol. Sci./Am. Physiol. Soc.",

keywords = "body weight, cancer patients, morbidity, mortality, tumor, host factors, tissue catabolism, cachexia, upregulation, skeletal muscle, adipose tissue",

author = "Tisdale, \{Michael J.\}",

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language = "English",

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pages = "340--348",

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N2 - Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue. ©2005 Int. Union Physiol. Sci./Am. Physiol. Soc.

AB - Loss of body weight in cancer patients strongly influences morbidity and mortality. Recent studies have suggested that both tumor and host factors play a major role in tissue catabolism in cachexia, leading to upregulation of degradative pathways in both skeletal muscle and adipose tissue. ©2005 Int. Union Physiol. Sci./Am. Physiol. Soc.

KW - body weight

KW - cancer patients

KW - morbidity

KW - mortality

KW - tumor

KW - host factors

KW - tissue catabolism

KW - cachexia

KW - upregulation

KW - skeletal muscle

KW - adipose tissue

UR - https://www.scopus.com/pages/publications/26844582185

UR - http://physiologyonline.physiology.org/content/20/5/340.long

U2 - 10.1152/physiol.00019.2005

DO - 10.1152/physiol.00019.2005

M3 - Article

C2 - 16174873

SN - 1548-9213

VL - 20

SP - 340

EP - 348

JO - Physiology

JF - Physiology

IS - 5

ER -

Molecular pathways leading to cancer cachexia

Abstract

UN SDGs

Keywords

Access to Document

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