Monitoring of temperature-mediated phase transitions of adipose tissue by combined optical coherence tomography and Abbe refractometry

Irina Y. Yanina*, Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski, Valery V. Tuchin

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Observation of temperature-mediated phase transitions between lipid components of the adipose tissues has been performed by combined use of the Abbe refractometry and optical coherence tomography. The phase transitions of the lipid components were clearly observed in the range of temperatures from 24°C to 60°C, and assessed by quantitatively monitoring the changes of the refractive index of 1-to 2-mm-thick porcine fat tissue slices. The developed approach has a great potential as an alternative method for obtaining accurate information on the processes occurring during thermal lipolysis.

Original languageEnglish
Article number016003
JournalJournal of Biomedical Optics
Volume23
Issue number1
Early online date2 Jan 2018
DOIs
Publication statusE-pub ahead of print - 2 Jan 2018

Bibliographical note

© 2018 Society of Photo-Optical

Keywords

  • Abbe refractometry
  • adipose tissue
  • heating
  • lipolysis
  • optical coherence tomography
  • phase transition
  • refractive index

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