Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 15-22 |
| Number of pages | 8 |
| Journal | Journal of Molecular and Cellular Cardiology |
| Volume | 47 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2009 |
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Bibliographical note
NOTICE: this is the author’s version of a work that was accepted for publication in Journal of molecular and cellular cardiology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Akki, A, Zhang, M, Murdoch, C, Brewer, A & Shah, AM, 'NADPH oxidase signaling and cardiac myocyte function' Journal of molecular and cellular cardiology, vol. 47, no. 1 (2009) DOI http://dx.doi.org/10.1016/j.yjmcc.2009.04.004Keywords
- NADPH oxidase
- Redox
- remodeling
- hypertrophy
- contraction
- signaling
- cardiac myocytes
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NADPH oxidase signaling and cardiac myocyte function. / Akki, Ashwin; Zhang, Min; Murdoch, Colin; Brewer, Alison; Shah, Ajay M.
In: Journal of Molecular and Cellular Cardiology, Vol. 47, No. 1, 07.2009, p. 15-22.Research output: Contribution to journal › Book/Film/Article review
TY - JOUR
T1 - NADPH oxidase signaling and cardiac myocyte function
AU - Akki, Ashwin
AU - Zhang, Min
AU - Murdoch, Colin
AU - Brewer, Alison
AU - Shah, Ajay M.
N1 - NOTICE: this is the author’s version of a work that was accepted for publication in Journal of molecular and cellular cardiology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Akki, A, Zhang, M, Murdoch, C, Brewer, A & Shah, AM, 'NADPH oxidase signaling and cardiac myocyte function' Journal of molecular and cellular cardiology, vol. 47, no. 1 (2009) DOI http://dx.doi.org/10.1016/j.yjmcc.2009.04.004
PY - 2009/7
Y1 - 2009/7
N2 - The NADPH oxidase family of enzymes has emerged as a major source of reactive oxygen species (ROS) that is important in diverse cellular functions including anti-microbial defence, inflammation and redox signaling. Of the five known NADPH oxidase isoforms, several are expressed in cardiovascular cells where they are involved in physiological and pathological processes such as the regulation of vascular tone, cell growth, migration, proliferation, hypertrophy, apoptosis and matrix deposition. This article reviews current knowledge regarding the role of NADPH oxidases in cardiomyocyte function in health and disease.
AB - The NADPH oxidase family of enzymes has emerged as a major source of reactive oxygen species (ROS) that is important in diverse cellular functions including anti-microbial defence, inflammation and redox signaling. Of the five known NADPH oxidase isoforms, several are expressed in cardiovascular cells where they are involved in physiological and pathological processes such as the regulation of vascular tone, cell growth, migration, proliferation, hypertrophy, apoptosis and matrix deposition. This article reviews current knowledge regarding the role of NADPH oxidases in cardiomyocyte function in health and disease.
KW - NADPH oxidase
KW - Redox
KW - remodeling
KW - hypertrophy
KW - contraction
KW - signaling
KW - cardiac myocytes
UR - http://www.scopus.com/inward/record.url?scp=67349118194&partnerID=8YFLogxK
U2 - 10.1016/j.yjmcc.2009.04.004
DO - 10.1016/j.yjmcc.2009.04.004
M3 - Book/Film/Article review
AN - SCOPUS:67349118194
VL - 47
SP - 15
EP - 22
JO - Journal of Molecular and Cellular Cardiology
JF - Journal of Molecular and Cellular Cardiology
SN - 0022-2828
IS - 1
ER -