TY - JOUR
T1 - Neurobiology of the premonitory urge in Tourette’s syndrome
T2 - pathophysiology and treatment implications
AU - Cavanna, Andrea E.
AU - Black, Kevin J.
AU - Hallett, Mark
AU - Voon, Valerie
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PY - 2017/3/1
Y1 - 2017/3/1
N2 - Motor and vocal tics are relatively common motor manifestations identified as the core features of Tourette’s syndrome (TS). Although traditional descriptions have focused on objective phenomenological observations, such as anatomical location, number and frequency of tics, patients’ first-person accounts have consistently reported characteristic subjective correlates. These sensory phenomena are often described as a feeling of mounting inner tension or urge to move (“premonitory urge”), which is transiently relieved by tic expression. This article reviews the existing literature on the clinical and neurobiological aspects of the premonitory urge in patients with TS, with focus on its pathophysiology and possible treatment implications.
AB - Motor and vocal tics are relatively common motor manifestations identified as the core features of Tourette’s syndrome (TS). Although traditional descriptions have focused on objective phenomenological observations, such as anatomical location, number and frequency of tics, patients’ first-person accounts have consistently reported characteristic subjective correlates. These sensory phenomena are often described as a feeling of mounting inner tension or urge to move (“premonitory urge”), which is transiently relieved by tic expression. This article reviews the existing literature on the clinical and neurobiological aspects of the premonitory urge in patients with TS, with focus on its pathophysiology and possible treatment implications.
UR - http://neuro.psychiatryonline.org/doi/10.1176/appi.neuropsych.16070141
UR - http://www.scopus.com/inward/record.url?scp=85018857817&partnerID=8YFLogxK
U2 - 10.1176/appi.neuropsych.16070141
DO - 10.1176/appi.neuropsych.16070141
M3 - Article
AN - SCOPUS:85018857817
SN - 0895-0172
VL - 29
SP - 95
EP - 104
JO - Journal of Neuropsychiatry and Clinical Neurosciences
JF - Journal of Neuropsychiatry and Clinical Neurosciences
IS - 2
ER -