TY - JOUR
T1 - Neuroleptic malignant syndrome and acute motor axonal neuropathy after Campylobacter jejuni infection
AU - Rajabally, Y. A.
AU - Ramlackhansingh, A.
AU - Fraser, M.
AU - Abbott, R. J.
PY - 2009/8
Y1 - 2009/8
N2 - We report the case of a patient with Parkinson's disease who developed rapidly progressive weakness of the four limbs due to an acute motor axonal neuropathy (AMAN). This occurred days after a neuroleptic malignant syndrome (NMS). Serologic evidence of a preceding Campylobacter jejuni infection was detected and treatment with intravenous immunoglobulins proved effective. This case suggests that the rarely described neuropathies occurring with NMS may have a postinfectious immune basis and respond to immunomodulatory therapy.
AB - We report the case of a patient with Parkinson's disease who developed rapidly progressive weakness of the four limbs due to an acute motor axonal neuropathy (AMAN). This occurred days after a neuroleptic malignant syndrome (NMS). Serologic evidence of a preceding Campylobacter jejuni infection was detected and treatment with intravenous immunoglobulins proved effective. This case suggests that the rarely described neuropathies occurring with NMS may have a postinfectious immune basis and respond to immunomodulatory therapy.
KW - Acute motor axonal neuropathy
KW - Campylobacter jejuni
KW - Guillain-Barré syndrome
KW - Neuroleptic malignant syndrome
KW - Parkinson's disease
UR - http://www.scopus.com/inward/record.url?scp=69049107555&partnerID=8YFLogxK
UR - https://www.sciencedirect.com/science/article/pii/S0987705309000318?via%3Dihub
U2 - 10.1016/j.neucli.2009.02.001
DO - 10.1016/j.neucli.2009.02.001
M3 - Article
C2 - 19716463
AN - SCOPUS:69049107555
SN - 0987-7053
VL - 39
JO - Neurophysiologie Clinique
JF - Neurophysiologie Clinique
IS - 3
ER -