Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

Barbara Wegiel, David J. Gallo, Kathleen G. Raman, Jenny M. Karlsson, Brett Ozanich, Beek Y. Chin, Edith Tzeng, Shakil Ahmad, Asif Ahmed, Catherine J. Baty, Leo E. Otterbein

Research output: Contribution to journalArticle

Abstract

Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.
LanguageEnglish
Pages537-548
Number of pages12
JournalCirculation
Volume121
Issue number4
DOIs
Publication statusPublished - Feb 2010

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Vascular System Injuries
Carbon Monoxide
Nitric Oxide
Bone Marrow
Balloon Angioplasty
Vascular Smooth Muscle
Smooth Muscle Myocytes
Blood Vessels
Pathologic Constriction

Bibliographical note

© 2010 American Heart Association, Inc.

Keywords

  • angioplasty
  • endothelium
  • nitric oxide synthase
  • signal transduction
  • stenosis

Cite this

Wegiel, B., Gallo, D. J., Raman, K. G., Karlsson, J. M., Ozanich, B., Chin, B. Y., ... Otterbein, L. E. (2010). Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. Circulation, 121(4), 537-548. https://doi.org/10.1161/CIRCULATIONAHA.109.887695
Wegiel, Barbara ; Gallo, David J. ; Raman, Kathleen G. ; Karlsson, Jenny M. ; Ozanich, Brett ; Chin, Beek Y. ; Tzeng, Edith ; Ahmad, Shakil ; Ahmed, Asif ; Baty, Catherine J. ; Otterbein, Leo E. / Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. In: Circulation. 2010 ; Vol. 121, No. 4. pp. 537-548.
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Wegiel, B, Gallo, DJ, Raman, KG, Karlsson, JM, Ozanich, B, Chin, BY, Tzeng, E, Ahmad, S, Ahmed, A, Baty, CJ & Otterbein, LE 2010, 'Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury' Circulation, vol. 121, no. 4, pp. 537-548. https://doi.org/10.1161/CIRCULATIONAHA.109.887695

Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury. / Wegiel, Barbara; Gallo, David J.; Raman, Kathleen G.; Karlsson, Jenny M.; Ozanich, Brett; Chin, Beek Y.; Tzeng, Edith; Ahmad, Shakil; Ahmed, Asif; Baty, Catherine J.; Otterbein, Leo E.

In: Circulation, Vol. 121, No. 4, 02.2010, p. 537-548.

Research output: Contribution to journalArticle

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T1 - Nitric oxide-dependent bone marrow progenitor mobilization by carbon monoxide enhances endothelial repair after vascular injury

AU - Wegiel, Barbara

AU - Gallo, David J.

AU - Raman, Kathleen G.

AU - Karlsson, Jenny M.

AU - Ozanich, Brett

AU - Chin, Beek Y.

AU - Tzeng, Edith

AU - Ahmad, Shakil

AU - Ahmed, Asif

AU - Baty, Catherine J.

AU - Otterbein, Leo E.

N1 - © 2010 American Heart Association, Inc.

PY - 2010/2

Y1 - 2010/2

N2 - Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.

AB - Carbon monoxide (CO) has emerged as a vascular homeostatic molecule that prevents balloon angioplasty-induced stenosis via antiproliferative effects on vascular smooth muscle cells. The effects of CO on reendothelialization have not been evaluated.

KW - angioplasty

KW - endothelium

KW - nitric oxide synthase

KW - signal transduction

KW - stenosis

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UR - http://circ.ahajournals.org/content/121/4/537

U2 - 10.1161/CIRCULATIONAHA.109.887695

DO - 10.1161/CIRCULATIONAHA.109.887695

M3 - Article

VL - 121

SP - 537

EP - 548

JO - Circulation

T2 - Circulation

JF - Circulation

SN - 0009-7322

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ER -