Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

O. Stelmashchuk, E. Zherebtsov, A. Zherebtsova, E. Kuznetsova, A. Vinokurov, A. Dunaev, A. Mamoshin, I. Snimshchikova, A. Borsukov, A. Bykov, I. Meglinski

Research output: Contribution to journalConference articlepeer-review

Abstract

The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive diagnostic system "LAKK-M" (SPE "LAZMA" Ltd, Russia) was used as the measuring equipment.

Original languageEnglish
Article number1033604
JournalProceedings of SPIE - International Society for Optical Engineering
Volume10336
DOIs
Publication statusPublished - 24 Mar 2017
Event4th International Symposium on Optics and Biophotonics, SFM 2016 - Saratov, Russian Federation
Duration: 27 Sep 201630 Sep 2016

Bibliographical note

Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

  • Fluorescence spectroscopy
  • Fluorescent label
  • Liposomal nanoparticles
  • Non-invasive control
  • Polyethylene glycol
  • Transport function

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