Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

O. Stelmashchuk; E. Zherebtsov; A. Zherebtsova; E. Kuznetsova; A. Vinokurov; A. Dunaev; A. Mamoshin; I. Snimshchikova; A. Borsukov; A. Bykov; I. Meglinski

doi:10.1117/12.2269379

Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

O. Stelmashchuk, E. Zherebtsov, A. Zherebtsova, E. Kuznetsova, A. Vinokurov, A. Dunaev, A. Mamoshin, I. Snimshchikova, A. Borsukov, A. Bykov, I. Meglinski

Research output: Contribution to journal › Conference article › peer-review

2 Citations (Scopus)

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Abstract

The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive diagnostic system "LAKK-M" (SPE "LAZMA" Ltd, Russia) was used as the measuring equipment.

Original language	English
Article number	1033604
Journal	Proceedings of SPIE - International Society for Optical Engineering
Volume	10336
DOIs	https://doi.org/10.1117/12.2269379
Publication status	Published - 24 Mar 2017
Event	4th International Symposium on Optics and Biophotonics, SFM 2016 - Saratov, Russian Federation Duration: 27 Sept 2016 → 30 Sept 2016

Bibliographical note

Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Funding

The work was supported by grant of the President of the Russian Federation for state support of young Russian scientists No MK-7168.2016.8 and by the state task of the Ministry of Education and Science, Russian Federation, for the Orel State University named after I.S. Turgenev. Authors acknowledge the support of the Academy of Finland (grants: 296408 and 290596).

Keywords

Fluorescence spectroscopy
Fluorescent label
Liposomal nanoparticles
Non-invasive control
Polyethylene glycol
Transport function

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Stelmashchuk, O., Zherebtsov, E., Zherebtsova, A., Kuznetsova, E., Vinokurov, A., Dunaev, A., Mamoshin, A., Snimshchikova, I., Borsukov, A., Bykov, A., & Meglinski, I. (2017). Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles. Proceedings of SPIE - International Society for Optical Engineering, 10336, Article 1033604. https://doi.org/10.1117/12.2269379

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note = "Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. ; 4th International Symposium on Optics and Biophotonics, SFM 2016 ; Conference date: 27-09-2016 Through 30-09-2016",

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Stelmashchuk, O, Zherebtsov, E, Zherebtsova, A, Kuznetsova, E, Vinokurov, A, Dunaev, A, Mamoshin, A, Snimshchikova, I, Borsukov, A, Bykov, A & Meglinski, I 2017, 'Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles', Proceedings of SPIE - International Society for Optical Engineering, vol. 10336, 1033604. https://doi.org/10.1117/12.2269379

Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles. / Stelmashchuk, O.; Zherebtsov, E.; Zherebtsova, A. et al.
In: Proceedings of SPIE - International Society for Optical Engineering, Vol. 10336, 1033604, 24.03.2017.

Research output: Contribution to journal › Conference article › peer-review

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T1 - Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

AU - Stelmashchuk, O.

AU - Zherebtsov, E.

AU - Zherebtsova, A.

AU - Kuznetsova, E.

AU - Vinokurov, A.

AU - Dunaev, A.

AU - Mamoshin, A.

AU - Snimshchikova, I.

AU - Borsukov, A.

AU - Bykov, A.

AU - Meglinski, I.

N1 - Copyright 2017 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2017/3/24

Y1 - 2017/3/24

N2 - The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive diagnostic system "LAKK-M" (SPE "LAZMA" Ltd, Russia) was used as the measuring equipment.

AB - The studies were carried out on groups of clinically healthy mice line of outbred CD-1 stock. The model animals were divided into 2 groups and received experimental liposomal formulations. Using the method of fluorescence spectroscopy, we investigated the effectiveness of penetration into the circulatory system of fluorescently stained liposomes with polyethylene glycol (PEG) and without PEG when administered orally. Fluorescence channel with a fiber probe series of multifunctional laser non-invasive diagnostic system "LAKK-M" (SPE "LAZMA" Ltd, Russia) was used as the measuring equipment.

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KW - Fluorescent label

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KW - Non-invasive control

KW - Polyethylene glycol

KW - Transport function

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JO - Proceedings of SPIE - International Society for Optical Engineering

JF - Proceedings of SPIE - International Society for Optical Engineering

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Y2 - 27 September 2016 through 30 September 2016

ER -

Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

Abstract

Bibliographical note

Funding

Keywords

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