Noninvasive control of rhodamine-loaded capsules distribution in vivo

Olga Stelmashchuk, Y Tarakanchikova, E Seryogina, G Piavchenko, Evgeny Zherebtsov, Andrey V. Dunaev, A Popov, Igor Meglinski

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Using fluorescence spectroscopy system with fibre-optical probe, we investigated the dynamics of propagation and circulation in the microcirculatory system of experimental nanocapsules fluorescent-labelled (rhodamine TRITC) nanocapsules. The studies were carried out in clinically healthy Wistar rats. The model animals were divided into control group and group received injections of the nanocapsules. The fluorescent measurements conducted transcutaneously on the thigh surface. The administration of the preparation with the rhodamine concentration of 5 mg/kg of animal weight resulted in twofold increase of fluorescence intensity by reference to the baseline level. As a result of the study, it was concluded that fluorescence spectroscopy can be used for transdermal measurements of the rhodamine-loaded capsules in vivo.
Original languageEnglish
Title of host publicationProceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX
PublisherSPIE
Volume10716
DOIs
Publication statusPublished - 26 Apr 2018
EventFall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX - , Russian Federation
Duration: 26 Sep 201730 Sep 2017

Publication series

NameProceedings of SPIE
PublisherSPIE
Volume10716
ISSN (Print)0277-786X

Conference

ConferenceFall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX
CountryRussian Federation
Period26/09/1730/09/17

Fingerprint

Nanocapsules
Rhodamines
Capsules
Fluorescence spectroscopy
Animals
Rats
Optical fibers
Fluorescence

Bibliographical note

Copyright 2018 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Cite this

Stelmashchuk, O., Tarakanchikova, Y., Seryogina, E., Piavchenko, G., Zherebtsov, E., Dunaev, A. V., ... Meglinski, I. (2018). Noninvasive control of rhodamine-loaded capsules distribution in vivo. In Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX (Vol. 10716). [1071619 ] (Proceedings of SPIE; Vol. 10716). SPIE. https://doi.org/10.1117/12.2315773
Stelmashchuk, Olga ; Tarakanchikova, Y ; Seryogina, E ; Piavchenko, G ; Zherebtsov, Evgeny ; Dunaev, Andrey V. ; Popov, A ; Meglinski, Igor. / Noninvasive control of rhodamine-loaded capsules distribution in vivo. Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX. Vol. 10716 SPIE, 2018. (Proceedings of SPIE).
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Stelmashchuk, O, Tarakanchikova, Y, Seryogina, E, Piavchenko, G, Zherebtsov, E, Dunaev, AV, Popov, A & Meglinski, I 2018, Noninvasive control of rhodamine-loaded capsules distribution in vivo. in Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX. vol. 10716, 1071619 , Proceedings of SPIE, vol. 10716, SPIE, Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, Russian Federation, 26/09/17. https://doi.org/10.1117/12.2315773

Noninvasive control of rhodamine-loaded capsules distribution in vivo. / Stelmashchuk, Olga; Tarakanchikova, Y; Seryogina, E; Piavchenko, G; Zherebtsov, Evgeny; Dunaev, Andrey V.; Popov, A; Meglinski, Igor.

Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX. Vol. 10716 SPIE, 2018. 1071619 (Proceedings of SPIE; Vol. 10716).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Stelmashchuk O, Tarakanchikova Y, Seryogina E, Piavchenko G, Zherebtsov E, Dunaev AV et al. Noninvasive control of rhodamine-loaded capsules distribution in vivo. In Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX. Vol. 10716. SPIE. 2018. 1071619 . (Proceedings of SPIE). https://doi.org/10.1117/12.2315773