Novel nano-biomaterials for inhibition of respiratory syncytial virus

Sameer Joshi, Daniel Kirby, Yvonne Perrie, Shree R. Singh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Respiratory syncytial virus (RSV) infection is a major concern for the population across all age groups and it is the single serotype with two major antigenic subgroups circulating together but one leads [1]. Considering published outcomes related to treatment, as well as the impact of RSV on global healthcare, a promising treatment or vaccine development remains a priority. The potential of liposomes as a carrier of active pharmacological agents was described decades ago [2-4] whilst liposomes have attracted much attention for their ability to carry antigens as well as immunomodulators [5]. Therefore, the work in this paper was aimed to prepare liposomes < 100 nm using thin film hydration followed by sonication, to effectively conjugate the anti-RSV peptide RF-482 and investigate the efficiency the liposomal formulation in presence and absence peptide RF-482 to inhibit RSV spread.

Original languageEnglish
Title of host publicationBiotech, Biomaterials and Biomedical - TechConnect Briefs 2017
Pages75-78
Number of pages4
Volume3
ISBN (Electronic)9780998878201
Publication statusPublished - 1 Jan 2017
Event11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference - Washington, United States
Duration: 14 May 201717 May 2017

Conference

Conference11th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 20th Annual Nanotech Conference and Expo, and the 2017 National SBIR/STTR Conference
CountryUnited States
CityWashington
Period14/05/1717/05/17

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Bibliographical note

© 2017 TechConnect.

Keywords

  • Liposomes
  • Peptide
  • RSV

Cite this

Joshi, S., Kirby, D., Perrie, Y., & Singh, S. R. (2017). Novel nano-biomaterials for inhibition of respiratory syncytial virus. In Biotech, Biomaterials and Biomedical - TechConnect Briefs 2017 (Vol. 3, pp. 75-78)