Ocular biotribology and the contact lens: Surface interactions and ocular response

A. Mann*, B.J. Tighe

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Biotribology is essentially the study of friction, lubrication and wear in biological systems. The area has been widely studied in relation to the behaviour of synovial joints and the design and behaviour of hip joint prostheses, but only in the last decade have serious studies been extended to the eye. In the ocular environment - as distinct from articular joints - wear is not a major factor. Both lubrication and friction are extremely important, however; this is particularly the case in the presence of the contact lens, which is a medical device important not only in vision correction but also as a therapeutic bandage for the compromised cornea. This chapter describes the difficulty in replicating experimental conditions that accurately reflect the complex nature of the ocular environment together with the factors such as load and rate of travel of the eyelid, which is the principal moving surface in the eye. Results obtained across a range of laboratories are compared.

Original languageEnglish
Title of host publicationBiomaterials and regenerative medicine in ophthalmology
EditorsTraian V. Chirila, Damien G. Harkin
Place of PublicationLondon (UK)
PublisherWoodhead
Pages45-74
Number of pages30
Edition2nd
ISBN (Electronic)978-0-08-100184-4
ISBN (Print)978-0-08-100147-9
DOIs
Publication statusPublished - 21 Apr 2016

Publication series

NameWoodhead Publishing Series in Biomaterials
PublisherWoodhead Publishing
Number112

Keywords

  • biomarkers
  • boundary lubrication
  • coefficient of friction
  • contact lenses
  • lens comfort

Fingerprint Dive into the research topics of 'Ocular biotribology and the contact lens: Surface interactions and ocular response'. Together they form a unique fingerprint.

  • Research Output

    Physicochemical properties of hydrogels for use in ophthalmology

    Tighe, B. J. & Mann, A., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 75-100 26 p. (Woodhead Publishing Series in Biomaterials; no. 112).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • The ageing ocular surface: challenges for biomaterials design and function

    Mann, A., Campbell, D. & Tighe, B. J., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 17-43 27 p. (Woodhead Publishing Series in Biomaterials; no. 112).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • The development of biomaterials for contact lens applications: effects of wear modality on materials design

    Tighe, B. J. & Mann, A., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 369-399 31 p. (Woodhead Publishing Series in Biomaterials; no. 112).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Cite this

    Mann, A., & Tighe, B. J. (2016). Ocular biotribology and the contact lens: Surface interactions and ocular response. In T. V. Chirila, & D. G. Harkin (Eds.), Biomaterials and regenerative medicine in ophthalmology (2nd ed., pp. 45-74). (Woodhead Publishing Series in Biomaterials; No. 112). Woodhead. https://doi.org/10.1016/B978-0-08-100147-9.00003-1