The paper describes the methodology and technical implementation of a multimodal approach for optical diagnostics in hepatopancreatobiliary organs focal and diffuse neoplasms. Fine needle aspiration biopsy technique and following cytological examination show its effectiveness and safety but its performing takes several days. However, the problem of real-time analysis of pathological changes in tissues remains relevant. The solution suggested is implementing of optical biopsy methods (namely fluorescence spectroscopy and diffuse reflectance spectroscopy) in the form of fiber-optic probe compatible with standard biopsy fine needles. The special device was designed for this purpose to conduct optical measurements and compare the results with ones obtained by conventional biopsy. The proposed methodology seems promising for developing new diagnostic criteria for clinical practice.
|Journal||Optics InfoBase Conference Papers|
|Publication status||Published - 22 Jul 2019|
|Event||European Conference on Biomedical Optics, ECBO_2019 - Munich, Netherlands|
Duration: 23 Jun 2019 → 25 Jun 2019
Bibliographical noteCopyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
- Diffuse reflectance spectroscopy
- Fine-needle aspiration biopsy
- Fluorescence spectroscopy
- Minimally invasive surgery
- Optical biopsy