Optical Properties of Perfused Rat Liver Tissues

Ksenia Kandurova*, Alexander Palalov, Evgeniya Seryogina, Viktor Dremin, Andrey Dunaev, Elena Potapova

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In this work, we demonstrate the results of measuring the optical properties of rat liver tissue slices after the liver itself underwent the perfusion procedure with an isotonic solution. The approach is suggested as a means to attenuate the influence of blood absorption on recorded characteristics and demonstrates its effectiveness in changing the composition of recorded spectra in the visible range. The data obtained seem promising to be used to upgrade the proposed methodology and apply the results for the diagnosis and modeling of light-tissue interaction in liver under healthy and pathological conditions.

Original languageEnglish
Article number010301
Number of pages7
JournalJournal of Biomedical Photonics and Engineering
Volume9
Issue number1
Early online date9 Dec 2022
DOIs
Publication statusPublished - 2023

Bibliographical note

Copyright © 2022, Journal of Biomedical Photonics & Engineering. This work is licensed under a Creative Commons Attribution 4.0 International License [https://creativecommons.org/licenses/by/4.0/. Funding Information: The authors acknowledge the support of the Russian Science Foundation under project No. 21-15-00325.

Keywords

  • liver
  • optical properties
  • perfusion
  • spectrophotometry

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