Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies

R.X. Foong, R. Meyer, H. Godwin, R. Dziubak, A.C. Lozinsky, K. Reeve, R. Knibb, N. Shah

Research output: Contribution to journalArticle

Abstract

BACKGROUND: Food allergy can have a significant impact on health related quality of life (HRQoL). Parental proxy questionnaires are commonly used when children are too young to complete questionnaires themselves. Little data is available on HRQoL in children with non-IgE-mediated gastrointestinal food allergy (GIFA). The aim of this study was to evaluate HRQoL in these children by parent proxy.

METHODS: A cross-sectional questionnaire study was conducted with children 2-16 years old with confirmed (GIFA). Parents of these children completed the Paediatric Quality of Life Inventory (PedsQL(™) ) and the Family Impact module of the PedsQL. The PedsQL scores were compared to two published cohorts: functional abdominal pain (FAP) and IgE-mediated food allergy.

RESULTS: Fifty-two parents of children with GIFA completed the PedsQL(™) parent proxy. The GIFA cohort had significantly better overall HRQoL compared to the FAP cohort, but lower emotional functioning scores. The GIFA cohort also had poorer physical QoL compared to the IgE cohort (all p<0.05). The more foods excluded, comorbidity of nasal congestion, abdominal pain, back arching, the persistence of flatus and gastrointestinal symptom severity after elimination diet were related to poorer QoL in this non-IgE cohort. Regression analyses showed that number of foods and nasal congestion significantly predicted total QoL score as perceived by parents.

CONCLUSIONS: This study has shown that different areas of HRQoL of children with GIFA are affected compared to children with FAP or IgE-mediated food allergy, highlighting the need for a specific GIFA HRQoL questionnaire to better understand the impact on these children. This article is protected by copyright. All rights reserved.

LanguageEnglish
Pages251-256
Number of pages6
JournalPaediatric Allergy and Immunology
Volume28
Issue number3
Early online date19 Dec 2016
DOIs
Publication statusPublished - May 2017

Fingerprint

Food Hypersensitivity
Hypersensitivity
Quality of Life
Abdominal Pain
Proxy
Immunoglobulin E
Parents
Nose
Flatulence
Food
Comorbidity
Cross-Sectional Studies
Regression Analysis
Pediatrics
Diet
Equipment and Supplies

Bibliographical note

This is the peer reviewed version of the following article: Foong, R. X., Meyer, R., Godwin, H., Dziubak, R., Lozinsky, A. C., Reeve, K., ... Shah, N. (2017). Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies. Paediatric Allergy and Immunology, 28(3), 251-256, which has been published in final form at http://dx.doi.org/10.1111/pai.12689. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

Keywords

  • gastrointestinal allergies
  • non-IgE-mediated allergies
  • paediatrics
  • quality of life

Cite this

Foong, R.X. ; Meyer, R. ; Godwin, H. ; Dziubak, R. ; Lozinsky, A.C. ; Reeve, K. ; Knibb, R. ; Shah, N. / Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies. In: Paediatric Allergy and Immunology. 2017 ; Vol. 28, No. 3. pp. 251-256.
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Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies. / Foong, R.X.; Meyer, R.; Godwin, H.; Dziubak, R.; Lozinsky, A.C.; Reeve, K.; Knibb, R.; Shah, N.

In: Paediatric Allergy and Immunology, Vol. 28, No. 3, 05.2017, p. 251-256.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies

AU - Foong, R.X.

AU - Meyer, R.

AU - Godwin, H.

AU - Dziubak, R.

AU - Lozinsky, A.C.

AU - Reeve, K.

AU - Knibb, R.

AU - Shah, N.

N1 - This is the peer reviewed version of the following article: Foong, R. X., Meyer, R., Godwin, H., Dziubak, R., Lozinsky, A. C., Reeve, K., ... Shah, N. (2017). Parental perception of their child's Quality of Life in children with non-Immunoglobulin-E mediated gastrointestinal allergies. Paediatric Allergy and Immunology, 28(3), 251-256, which has been published in final form at http://dx.doi.org/10.1111/pai.12689. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

PY - 2017/5

Y1 - 2017/5

N2 - BACKGROUND: Food allergy can have a significant impact on health related quality of life (HRQoL). Parental proxy questionnaires are commonly used when children are too young to complete questionnaires themselves. Little data is available on HRQoL in children with non-IgE-mediated gastrointestinal food allergy (GIFA). The aim of this study was to evaluate HRQoL in these children by parent proxy.METHODS: A cross-sectional questionnaire study was conducted with children 2-16 years old with confirmed (GIFA). Parents of these children completed the Paediatric Quality of Life Inventory (PedsQL(™) ) and the Family Impact module of the PedsQL. The PedsQL scores were compared to two published cohorts: functional abdominal pain (FAP) and IgE-mediated food allergy.RESULTS: Fifty-two parents of children with GIFA completed the PedsQL(™) parent proxy. The GIFA cohort had significantly better overall HRQoL compared to the FAP cohort, but lower emotional functioning scores. The GIFA cohort also had poorer physical QoL compared to the IgE cohort (all p<0.05). The more foods excluded, comorbidity of nasal congestion, abdominal pain, back arching, the persistence of flatus and gastrointestinal symptom severity after elimination diet were related to poorer QoL in this non-IgE cohort. Regression analyses showed that number of foods and nasal congestion significantly predicted total QoL score as perceived by parents.CONCLUSIONS: This study has shown that different areas of HRQoL of children with GIFA are affected compared to children with FAP or IgE-mediated food allergy, highlighting the need for a specific GIFA HRQoL questionnaire to better understand the impact on these children. This article is protected by copyright. All rights reserved.

AB - BACKGROUND: Food allergy can have a significant impact on health related quality of life (HRQoL). Parental proxy questionnaires are commonly used when children are too young to complete questionnaires themselves. Little data is available on HRQoL in children with non-IgE-mediated gastrointestinal food allergy (GIFA). The aim of this study was to evaluate HRQoL in these children by parent proxy.METHODS: A cross-sectional questionnaire study was conducted with children 2-16 years old with confirmed (GIFA). Parents of these children completed the Paediatric Quality of Life Inventory (PedsQL(™) ) and the Family Impact module of the PedsQL. The PedsQL scores were compared to two published cohorts: functional abdominal pain (FAP) and IgE-mediated food allergy.RESULTS: Fifty-two parents of children with GIFA completed the PedsQL(™) parent proxy. The GIFA cohort had significantly better overall HRQoL compared to the FAP cohort, but lower emotional functioning scores. The GIFA cohort also had poorer physical QoL compared to the IgE cohort (all p<0.05). The more foods excluded, comorbidity of nasal congestion, abdominal pain, back arching, the persistence of flatus and gastrointestinal symptom severity after elimination diet were related to poorer QoL in this non-IgE cohort. Regression analyses showed that number of foods and nasal congestion significantly predicted total QoL score as perceived by parents.CONCLUSIONS: This study has shown that different areas of HRQoL of children with GIFA are affected compared to children with FAP or IgE-mediated food allergy, highlighting the need for a specific GIFA HRQoL questionnaire to better understand the impact on these children. This article is protected by copyright. All rights reserved.

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KW - non-IgE-mediated allergies

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KW - quality of life

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