TY - JOUR
T1 - PCOS remains a diagnosis of exclusion
T2 - a concise review of key endocrinopathies to exclude
AU - Kyritsi, Eleni Magdalini
AU - Dimitriadis, George K.
AU - Kyrou, Ioannis
AU - Kaltsas, Gregory
AU - Randeva, Harpal S.
N1 - This is the peer reviewed version of the following article: Kyritsi, E. M., Dimitriadis, G. K., Kyrou, I., Kaltsas, G., & Randeva, H. S. (2017). PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude. Clinical Endocrinology, 86 (1) 1-6, which has been published in final form at http://dx.doi.org/10.1111/cen.13245. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.
AB - Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.
UR - http://onlinelibrary.wiley.com/doi/10.1111/cen.13245/abstract
UR - http://www.scopus.com/inward/record.url?scp=84995947232&partnerID=8YFLogxK
U2 - 10.1111/cen.13245
DO - 10.1111/cen.13245
M3 - Review article
AN - SCOPUS:84995947232
SN - 0300-0664
VL - 86
SP - 1
EP - 6
JO - Clinical Endocrinology
JF - Clinical Endocrinology
IS - 1
ER -