PCOS remains a diagnosis of exclusion:   a concise review of key endocrinopathies to exclude

Eleni Magdalini Kyritsi; George K. Dimitriadis; Ioannis Kyrou; Gregory Kaltsas; Harpal S. Randeva

doi:10.1111/cen.13245

PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude

Eleni Magdalini Kyritsi
, George K. Dimitriadis
, Ioannis Kyrou
, Gregory Kaltsas
, Harpal S. Randeva^*

^*Corresponding author for this work

Aston Medical School

University of Warwick
Aston University
University Hospitals of Coventry and Warwickshire NHS Trust
National and Kapodistrian University of Athens
Imperial College London

Research output: Contribution to journal › Review article › peer-review

33 Citations (Scopus)

147 Downloads (Pure)

Abstract

Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Clinical Endocrinology
Volume	86
Issue number	1
Early online date	11 Oct 2016
DOIs	https://doi.org/10.1111/cen.13245
Publication status	Published - 1 Jan 2017

Bibliographical note

This is the peer reviewed version of the following article: Kyritsi, E. M., Dimitriadis, G. K., Kyrou, I., Kaltsas, G., & Randeva, H. S. (2017). PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude. Clinical Endocrinology, 86 (1) 1-6, which has been published in final form at http://dx.doi.org/10.1111/cen.13245. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1111/cen.13245

PCOS remains a diagnosis of exclusion
This is the peer reviewed version of the following article: Kyritsi, E. M., Dimitriadis, G. K., Kyrou, I., Kaltsas, G., & Randeva, H. S. (2017). PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude. Clinical Endocrinology, 86 (1) 1-6, which has been published in final form at http://dx.doi.org/10.1111/cen.13245. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Accepted author manuscript, 875 KB

Cite this

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title = "PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude",

abstract = "Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.",

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