Peptide recognition by the T cell receptor: comparison of binding free energies from thermodynamic integration, Poisson-Boltzmann and linear interaction energy approximations

Mathematics

• T Cell Receptor 100%
• Binding Energy 88%
• Peptides 80%
• Ludwig Boltzmann 63%
• Free Energy 60%
• Thermodynamics 59%
• Siméon Denis Poisson 45%
• Interaction 40%
• Energy 37%
• Major Histocompatibility Complex 34%
• Molecular Mechanics 33%
• Molecular Dynamics Simulation 29%
• Approximation 28%
• Tax 26%
• Vaccine 24%
• Surface area 22%
• Energy Method 20%
• Drugs 19%
• Simulation 11%
• Design 11%

Engineering & Materials Science

• T-cells 84%
• Peptides 74%
• Free energy 67%
• Thermodynamics 48%
• Molecular mechanics 30%
• Vaccines 25%
• Ligands 25%
• Taxation 21%
• Molecular dynamics 21%
• Computer simulation 10%

Physics & Astronomy

• peptides 62%
• free energy 45%
• thermodynamics 38%
• approximation 29%
• vaccines 22%
• interactions 22%
• energy 16%
• drugs 14%
• ligands 14%
• simulation 10%
• molecular dynamics 10%