Pharmacokinetics of a CCR5 inhibitor in rhesus macaques following vaginal, rectal and oral application

Keyphrases

• Pharmacokinetics 100%
• Rhesus Macaque 100%
• Vaginal Fluid 100%
• CCR5 Inhibitors 100%
• Oral Application 100%
• Vaginal Application 100%
• Rectal Fluid 100%
• Oral Administration 50%
• Hydroxyethylcellulose Gel 50%
• Blood Plasma 50%
• Route of Administration 25%
• Small Molecules 25%
• Human Immunodeficiency Virus Type 1 (HIV-1) 25%
• Silicone Elastomer 25%
• Vaginal Administration 25%
• HIV Microbicide 25%
• Vaginal Tissue 25%
• Depo-Provera 25%
• Antiretroviral 25%
• Fluid Concentration 25%
• Vaginal Ring 25%
• Matrix Classes 25%
• HIV Transmission 25%
• Transfer Path 25%
• Elastomeric Matrix 25%
• Drug Transfer 25%
• Rectal Administration 25%
• Local Administration 25%
• Oral Solution 25%
• Oral Pre-exposure Prophylaxis 25%
• HPLC-mass Spectrometry 25%
• Mucosal Sites 25%

Medicine and Dentistry

• Vaginal Discharge 100%
• Pharmacokinetics 100%
• Human Immunodeficiency Virus 66%
• Oral Drug Administration 66%
• Hydroxyethyl Cellulose 66%
• Blood Plasma 66%
• High-Performance Liquid Chromatography 33%
• Silastic 33%
• Antimicrobial Agent 33%
• Mass Spectrum 33%
• Drug Absorption 33%
• Depo-Provera 33%
• Pre-Exposure Prophylaxis 33%
• Vagina Ring 33%
• Intravaginal Administration 33%
• Rectal Administration 33%
• Medroxyprogesterone Acetate 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Pharmacokinetics 100%
• Vagina Discharge 100%
• Rhesus Monkey 100%
• HIV 66%
• Hydroxyethyl Cellulose 66%
• High Performance Liquid Chromatography 33%
• Antimicrobial Agent 33%
• Route of Administration 33%
• Silastic 33%
• Medroxyprogesterone Acetate 33%