Photoacoustic Imaging in Biomedicine and Life Sciences

Alexey Neprokin; Christian Broadway; Teemu Myllylä; Alexander Bykov; Igor Meglinski

doi:10.3390/life12040588

Photoacoustic Imaging in Biomedicine and Life Sciences

Alexey Neprokin
, Christian Broadway
, Teemu Myllylä
, Alexander Bykov
, Igor Meglinski^*

^*Corresponding author for this work

Opto-Electronics and Measurements, ITEE, University of Oulu, P.O. Box 4500, 90570 Oulu, Finland
Opto-Electronics and Measurements, ITEE, University of Oulu, P.O. Box 4500, 90570 Oulu, Finland; Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, P.O. Box 4500, 90014 Oulu, Finland

Research output: Contribution to journal › Review article › peer-review

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Abstract

Photo-acoustic imaging, also known as opto-acoustic imaging, has become a widely popular modality for biomedical applications. This hybrid technique possesses the advantages of high optical contrast and high ultrasonic resolution. Due to the distinct optical absorption properties of tissue compartments and main chromophores, photo-acoustics is able to non-invasively observe structural and functional variations within biological tissues including oxygenation and deoxygenation, blood vessels and spatial melanin distribution. The detection of acoustic waves produced by a pulsed laser source yields a high scaling range, from organ level photo-acoustic tomography to sub-cellular or even molecular imaging. This review discusses significant novel technical solutions utilising photo-acoustics and their applications in the fields of biomedicine and life sciences.

Original language	English
Article number	588
Journal	Life
Volume	12
Issue number	4
DOIs	https://doi.org/10.3390/life12040588
Publication status	Published - 14 Apr 2022

Bibliographical note

© 2022 by the authors.
Licensee MDPI, Basel, Switzerland.
This article is an open access article
distributed under the terms and
conditions of the Creative Commons
Attribution (CC BY) license (https://
creativecommons.org/licenses/by/
4.0/).

Keywords

photo-acoustics
opto-acoustic imaging
biomedical imaging
photo-acoustic tomography
photo-acoustic microscopy
photo-acoustic endoscopy

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10.3390/life12040588Licence: CC BY 4.0

Photoacoustic Imaging in Biomedicine and Life Sciences
© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
Final published version, 13 MBLicence: CC BY 4.0

Cite this

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title = "Photoacoustic Imaging in Biomedicine and Life Sciences",

abstract = "Photo-acoustic imaging, also known as opto-acoustic imaging, has become a widely popular modality for biomedical applications. This hybrid technique possesses the advantages of high optical contrast and high ultrasonic resolution. Due to the distinct optical absorption properties of tissue compartments and main chromophores, photo-acoustics is able to non-invasively observe structural and functional variations within biological tissues including oxygenation and deoxygenation, blood vessels and spatial melanin distribution. The detection of acoustic waves produced by a pulsed laser source yields a high scaling range, from organ level photo-acoustic tomography to sub-cellular or even molecular imaging. This review discusses significant novel technical solutions utilising photo-acoustics and their applications in the fields of biomedicine and life sciences.",

keywords = "photo-acoustics, opto-acoustic imaging, biomedical imaging, photo-acoustic tomography, photo-acoustic microscopy, photo-acoustic endoscopy",

author = "Alexey Neprokin and Christian Broadway and Teemu Myllyl{\"a} and Alexander Bykov and Igor Meglinski",

note = "{\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).",

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language = "English",

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AU - Neprokin, Alexey

AU - Broadway, Christian

AU - Myllylä, Teemu

AU - Bykov, Alexander

AU - Meglinski, Igor

N1 - © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

PY - 2022/4/14

Y1 - 2022/4/14

N2 - Photo-acoustic imaging, also known as opto-acoustic imaging, has become a widely popular modality for biomedical applications. This hybrid technique possesses the advantages of high optical contrast and high ultrasonic resolution. Due to the distinct optical absorption properties of tissue compartments and main chromophores, photo-acoustics is able to non-invasively observe structural and functional variations within biological tissues including oxygenation and deoxygenation, blood vessels and spatial melanin distribution. The detection of acoustic waves produced by a pulsed laser source yields a high scaling range, from organ level photo-acoustic tomography to sub-cellular or even molecular imaging. This review discusses significant novel technical solutions utilising photo-acoustics and their applications in the fields of biomedicine and life sciences.

AB - Photo-acoustic imaging, also known as opto-acoustic imaging, has become a widely popular modality for biomedical applications. This hybrid technique possesses the advantages of high optical contrast and high ultrasonic resolution. Due to the distinct optical absorption properties of tissue compartments and main chromophores, photo-acoustics is able to non-invasively observe structural and functional variations within biological tissues including oxygenation and deoxygenation, blood vessels and spatial melanin distribution. The detection of acoustic waves produced by a pulsed laser source yields a high scaling range, from organ level photo-acoustic tomography to sub-cellular or even molecular imaging. This review discusses significant novel technical solutions utilising photo-acoustics and their applications in the fields of biomedicine and life sciences.

KW - photo-acoustics

KW - opto-acoustic imaging

KW - biomedical imaging

KW - photo-acoustic tomography

KW - photo-acoustic microscopy

KW - photo-acoustic endoscopy

UR - https://www.mdpi.com/2075-1729/12/4/588

U2 - 10.3390/life12040588

DO - 10.3390/life12040588

M3 - Review article

SN - 2075-1729

VL - 12

JO - Life

JF - Life

IS - 4

M1 - 588

ER -

Photoacoustic Imaging in Biomedicine and Life Sciences

Abstract

Bibliographical note

Keywords

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