Food allergies can provoke severe clinical reactions. Within the FP7 project POSITIVE a Lab-on-a-Chip platform for label-free quantitative allergen testing is under development. The system integrates fluidic handling, optical interrogation and a porous Silicon based bio sensor cartridge. Optical and fluidic concepts have been derived and partially tested with positive results on lab bench level. Further effort has to be spent on higher system integration and miniaturization of the components as well as signal processing and data evaluation. Model tests based on the immobilization of allergens and molecular recognition by specific antibodies have been established proofing the pre-treated porous Silicon membranes bio assay suitability.
|Publication status||Published - 1 Jan 2012|
|Event||Smart Systems Integration Conference 2012, SSI 2012 - Zurich, Switzerland|
Duration: 21 Mar 2012 → 22 Mar 2012
|Conference||Smart Systems Integration Conference 2012, SSI 2012|
|Period||21/03/12 → 22/03/12|