TY - JOUR
T1 - Physical Properties and Interaction With the Ocular Surface of Water-Gradient Contact Lenses
AU - Ponzini, Erika
AU - Recchioni, Alberto
AU - Cheloni, Riccardo
AU - Zeri, Fabrizio
AU - Tavazzi, Silvia
N1 - Copyright © 2023 Contact Lens Association of Ophthalmologists. This is a pre-copyedited, author-produced version of an article accepted for publication in Eye & Contact Lens: Science & Clinical Practice. The published version of record, 'Ponzini et al. (2023) "Physical Properties and Interaction With the Ocular Surface of Water-Gradient Contact Lenses". Eye & Contact Lens: Science & Clinical Practice'. The published version of record can be found here: https://doi.org/10.1097/ICL.0000000000000974
PY - 2023/4/1
Y1 - 2023/4/1
N2 - Since the introduction of silicone hydrogel contact lenses, many silicone-hydrogel materials have been produced, including water-gradient contact lenses with a silicone hydrogel core and a thin hydrogel outer layer (e.g., delefilcon A, verofilcon A, and lehfilcon A). Their properties have been investigated in various studies assessing both the chemical-physical characteristics and the comfort, but the overall picture is not always consistent. In this study, water-gradient technology is reviewed by looking at basic physical properties both in vitro and in vivo and at the interaction with the human ocular surface. Surface and bulk dehydration, surface wetting and dewetting, shear stress, interaction with tear components and with other environmental compounds, and comfort are discussed.
AB - Since the introduction of silicone hydrogel contact lenses, many silicone-hydrogel materials have been produced, including water-gradient contact lenses with a silicone hydrogel core and a thin hydrogel outer layer (e.g., delefilcon A, verofilcon A, and lehfilcon A). Their properties have been investigated in various studies assessing both the chemical-physical characteristics and the comfort, but the overall picture is not always consistent. In this study, water-gradient technology is reviewed by looking at basic physical properties both in vitro and in vivo and at the interaction with the human ocular surface. Surface and bulk dehydration, surface wetting and dewetting, shear stress, interaction with tear components and with other environmental compounds, and comfort are discussed.
UR - https://journals.lww.com/claojournal/Fulltext/9900/Physical_Properties_and_Interaction_With_the.84.aspx
UR - http://www.scopus.com/inward/record.url?scp=85151042777&partnerID=8YFLogxK
U2 - 10.1097/ICL.0000000000000974
DO - 10.1097/ICL.0000000000000974
M3 - Review article
C2 - 36811833
SN - 1542-2321
VL - 49
SP - 152
EP - 159
JO - Eye & contact lens
JF - Eye & contact lens
IS - 4
ER -