Physicochemical properties of hydrogels for use in ophthalmology

B.J. Tighe*, A. Mann

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter deals with the physicochemical aspects of structure-property relationships in synthetic hydrogels, with particular reference to their application in optometry and ophthalmology. It demonstrates the ways in which the amount of water contained in the hydrogel network can be manipulated by changes in copolymer composition and illustrates the advantages and limitations imposed by use of water as a means of influencing surface, transport and mechanical properties of the gel. The chapter then illustrates how this basic understanding has formed a platform for the development of synthetic interpenetrating networks and macroporous materials, and of hybrids of natural and synthetic hydrogels. The behaviour of these more complex systems is not so centrally dominated by the equilibrium water content as is the case with homogeneous synthetic hydrogels, thus providing advantageous ways of extending the properties and applications of these interesting materials.

Original languageEnglish
Title of host publicationBiomaterials and regenerative medicine in ophthalmology
EditorsTraian V. Chirila, Damien G. Harkin
Place of PublicationLondon (UK)
PublisherWoodhead
Pages75-100
Number of pages26
Edition2nd
ISBN (Electronic)978-0-08-100184-4
ISBN (Print)978-0-08-100147-9
DOIs
Publication statusPublished - 21 Apr 2016

Publication series

NameWoodhead Publishing Series in Biomaterials
PublisherWoodhead Publishing
Number112

Keywords

  • equilibrium water content
  • hydrogels
  • interpenetrating networks
  • macroporous hydrogels
  • oxygen permeability
  • surface energy

Fingerprint Dive into the research topics of 'Physicochemical properties of hydrogels for use in ophthalmology'. Together they form a unique fingerprint.

  • Research Output

    Ocular biotribology and the contact lens: Surface interactions and ocular response

    Mann, A. & Tighe, B. J., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 45-74 30 p. (Woodhead Publishing Series in Biomaterials; no. 112).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • The ageing ocular surface: challenges for biomaterials design and function

    Mann, A., Campbell, D. & Tighe, B. J., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 17-43 27 p. (Woodhead Publishing Series in Biomaterials; no. 112).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • The development of biomaterials for contact lens applications: effects of wear modality on materials design

    Tighe, B. J. & Mann, A., 21 Apr 2016, Biomaterials and regenerative medicine in ophthalmology. Chirila, T. V. & Harkin, D. G. (eds.). 2nd ed. London (UK): Woodhead, p. 369-399 31 p. (Woodhead Publishing Series in Biomaterials; no. 112).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • Cite this

    Tighe, B. J., & Mann, A. (2016). Physicochemical properties of hydrogels for use in ophthalmology. In T. V. Chirila, & D. G. Harkin (Eds.), Biomaterials and regenerative medicine in ophthalmology (2nd ed., pp. 75-100). (Woodhead Publishing Series in Biomaterials; No. 112). Woodhead. https://doi.org/10.1016/B978-0-08-100147-9.00004-3