Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Lucy M. Watkins, Adam F. Lee*, James W.B. Moir, Karen Wilson

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

Original languageEnglish
Pages (from-to)88-94
Number of pages7
JournalACS Biomaterials Science and Engineering
Volume3
Issue number1
Early online date12 Dec 2016
DOIs
Publication statusPublished - 9 Jan 2017

Fingerprint

Alcohols
Plasmas
Plasma polymerization
Coatings
Polyurethanes
Biofilms
Fibroblasts
Cell culture
Scaffolds
Escherichia coli
Polymers
Adhesion
Monomers
allyl alcohol

Bibliographical note

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705

Keywords

  • biofilm
  • fibroblast
  • plasma
  • polymerization
  • polyurethane
  • XPS

Cite this

Watkins, L. M., Lee, A. F., Moir, J. W. B., & Wilson, K. (2017). Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment. ACS Biomaterials Science and Engineering, 3(1), 88-94. https://doi.org/10.1021/acsbiomaterials.6b00705
Watkins, Lucy M. ; Lee, Adam F. ; Moir, James W.B. ; Wilson, Karen. / Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment. In: ACS Biomaterials Science and Engineering. 2017 ; Vol. 3, No. 1. pp. 88-94.
@article{8c8e516b8ca1421cb5c918aaf7933027,
title = "Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment",
abstract = "Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.",
keywords = "biofilm, fibroblast, plasma, polymerization, polyurethane, XPS",
author = "Watkins, {Lucy M.} and Lee, {Adam F.} and Moir, {James W.B.} and Karen Wilson",
note = "This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright {\circledC} American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705",
year = "2017",
month = "1",
day = "9",
doi = "10.1021/acsbiomaterials.6b00705",
language = "English",
volume = "3",
pages = "88--94",
number = "1",

}

Watkins, LM, Lee, AF, Moir, JWB & Wilson, K 2017, 'Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment', ACS Biomaterials Science and Engineering, vol. 3, no. 1, pp. 88-94. https://doi.org/10.1021/acsbiomaterials.6b00705

Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment. / Watkins, Lucy M.; Lee, Adam F.; Moir, James W.B.; Wilson, Karen.

In: ACS Biomaterials Science and Engineering, Vol. 3, No. 1, 09.01.2017, p. 88-94.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

AU - Watkins, Lucy M.

AU - Lee, Adam F.

AU - Moir, James W.B.

AU - Wilson, Karen

N1 - This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705

PY - 2017/1/9

Y1 - 2017/1/9

N2 - Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

AB - Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

KW - biofilm

KW - fibroblast

KW - plasma

KW - polymerization

KW - polyurethane

KW - XPS

UR - http://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.6b00705

UR - http://www.scopus.com/inward/record.url?scp=85016253056&partnerID=8YFLogxK

U2 - 10.1021/acsbiomaterials.6b00705

DO - 10.1021/acsbiomaterials.6b00705

M3 - Article

AN - SCOPUS:85016253056

VL - 3

SP - 88

EP - 94

IS - 1

ER -

Watkins LM, Lee AF, Moir JWB, Wilson K. Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment. ACS Biomaterials Science and Engineering. 2017 Jan 9;3(1):88-94. https://doi.org/10.1021/acsbiomaterials.6b00705