Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Lucy M. Watkins, Adam F. Lee*, James W.B. Moir, Karen Wilson

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

Original languageEnglish
Pages (from-to)88-94
Number of pages7
JournalACS Biomaterials Science and Engineering
Volume3
Issue number1
Early online date12 Dec 2016
DOIs
Publication statusPublished - 9 Jan 2017

Bibliographical note

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705

Keywords

  • biofilm
  • fibroblast
  • plasma
  • polymerization
  • polyurethane
  • XPS

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