Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Lucy M. Watkins; Adam F. Lee; James W.B. Moir; Karen Wilson

doi:10.1021/acsbiomaterials.6b00705

Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Lucy M. Watkins, Adam F. Lee^*, James W.B. Moir, Karen Wilson

^*Corresponding author for this work

University of York

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

22 Downloads (Pure)

Abstract

Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

Original language	English
Pages (from-to)	88-94
Number of pages	7
Journal	ACS Biomaterials Science and Engineering
Volume	3
Issue number	1
Early online date	12 Dec 2016
DOIs	https://doi.org/10.1021/acsbiomaterials.6b00705
Publication status	Published - 9 Jan 2017

Bibliographical note

This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705

Keywords

biofilm
fibroblast
plasma
polymerization
polyurethane
XPS

Access to Document

10.1021/acsbiomaterials.6b00705

Plasma generated poly allyl alcohol antifouling coatings for cellular attachmentAccepted author manuscript, 542 KB

Cite this

@article{8c8e516b8ca1421cb5c918aaf7933027,

title = "Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment",

abstract = "Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.",

keywords = "biofilm, fibroblast, plasma, polymerization, polyurethane, XPS",

author = "Watkins, {Lucy M.} and Lee, {Adam F.} and Moir, {James W.B.} and Karen Wilson",

note = "This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright {\textcopyright} American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705",

year = "2017",

month = jan,

day = "9",

doi = "10.1021/acsbiomaterials.6b00705",

language = "English",

volume = "3",

pages = "88--94",

journal = "ACS Biomaterials Science and Engineering",

publisher = "American Chemical Society",

number = "1",

}

TY - JOUR

T1 - Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

AU - Watkins, Lucy M.

AU - Lee, Adam F.

AU - Moir, James W.B.

AU - Wilson, Karen

N1 - This document is the Accepted Manuscript version of a Published Work that appeared in final form in ACS Biomaterials Science and Engineering, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/acsbiomaterials.6b00705

PY - 2017/1/9

Y1 - 2017/1/9

N2 - Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

AB - Conformal poly(allyl alcohol) (PAA) coatings were grown on a biomedical grade polyurethane scaffold using pulsed plasma polymerization of the allyl alcohol monomer. The creation of a continuous wave polymer primer layer increases the interfacial adhesion and stability of a subsequent pulsed plasma deposited PAA film. The resulting PAA coatings are strongly hydrophilic and stable following 7 days incubation in biological media. Films prepared through this energyefficient, two-step process promote human dermal fibroblast cell culture, while resisting E. coli biofilm formation.

KW - biofilm

KW - fibroblast

KW - plasma

KW - polymerization

KW - polyurethane

KW - XPS

UR - http://pubs.acs.org/doi/abs/10.1021/acsbiomaterials.6b00705

UR - http://www.scopus.com/inward/record.url?scp=85016253056&partnerID=8YFLogxK

U2 - 10.1021/acsbiomaterials.6b00705

DO - 10.1021/acsbiomaterials.6b00705

M3 - Article

AN - SCOPUS:85016253056

VL - 3

SP - 88

EP - 94

JO - ACS Biomaterials Science and Engineering

JF - ACS Biomaterials Science and Engineering

IS - 1

ER -

Plasma-generated poly(allyl alcohol) antifouling coatings for cellular attachment

Abstract

Bibliographical note

Keywords

Access to Document

Other files and links

Fingerprint

Cite this