Potential role of anaerobic cocci in impaired human wound healing

Ivan B Wall; Charlotte E Davies; Katja E Hill; Melanie J Wilson; Phil Stephens; Keith G Harding; David W Thomas

doi:10.1046/j.1524-475X.2002.t01-1-10602.x

Potential role of anaerobic cocci in impaired human wound healing

Ivan B Wall, Charlotte E Davies, Katja E Hill, Melanie J Wilson, Phil Stephens, Keith G Harding, David W Thomas

Research output: Contribution to journal › Review article › peer-review

Abstract

Although more than 80% of infected and 70% of noninfected leg ulcers have been shown to harbor anaerobic organisms, their role in mediating impaired wound healing in the skin is frequently overlooked. There is now increasing evidence that the gram-positive anaerobic cocci play a role (both directly and indirectly) in mediating impaired wound healing in vivo. This article discusses the mechanisms by which these microorganisms may interfere with the inflammation, repair, and remodeling phases of the wound healing process.

Original language	English
Pages (from-to)	346-353
Number of pages	8
Journal	Wound Repair and Regeneration
Volume	10
Issue number	6
DOIs	https://doi.org/10.1046/j.1524-475X.2002.t01-1-10602.x
Publication status	Published - 28 Nov 2002

Keywords

Bacteria, Anaerobic/isolation & purification
Gram-Positive Bacterial Infections/complications
Gram-Positive Cocci/isolation & purification
Humans
Leg Ulcer/complications
Wound Healing/physiology

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10.1046/j.1524-475X.2002.t01-1-10602.x

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title = "Potential role of anaerobic cocci in impaired human wound healing",

abstract = "Although more than 80% of infected and 70% of noninfected leg ulcers have been shown to harbor anaerobic organisms, their role in mediating impaired wound healing in the skin is frequently overlooked. There is now increasing evidence that the gram-positive anaerobic cocci play a role (both directly and indirectly) in mediating impaired wound healing in vivo. This article discusses the mechanisms by which these microorganisms may interfere with the inflammation, repair, and remodeling phases of the wound healing process.",

keywords = "Bacteria, Anaerobic/isolation & purification, Gram-Positive Bacterial Infections/complications, Gram-Positive Cocci/isolation & purification, Humans, Leg Ulcer/complications, Wound Healing/physiology",

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T1 - Potential role of anaerobic cocci in impaired human wound healing

AU - Wall, Ivan B

AU - Davies, Charlotte E

AU - Hill, Katja E

AU - Wilson, Melanie J

AU - Stephens, Phil

AU - Harding, Keith G

AU - Thomas, David W

PY - 2002/11/28

Y1 - 2002/11/28

N2 - Although more than 80% of infected and 70% of noninfected leg ulcers have been shown to harbor anaerobic organisms, their role in mediating impaired wound healing in the skin is frequently overlooked. There is now increasing evidence that the gram-positive anaerobic cocci play a role (both directly and indirectly) in mediating impaired wound healing in vivo. This article discusses the mechanisms by which these microorganisms may interfere with the inflammation, repair, and remodeling phases of the wound healing process.

AB - Although more than 80% of infected and 70% of noninfected leg ulcers have been shown to harbor anaerobic organisms, their role in mediating impaired wound healing in the skin is frequently overlooked. There is now increasing evidence that the gram-positive anaerobic cocci play a role (both directly and indirectly) in mediating impaired wound healing in vivo. This article discusses the mechanisms by which these microorganisms may interfere with the inflammation, repair, and remodeling phases of the wound healing process.

KW - Bacteria, Anaerobic/isolation & purification

KW - Gram-Positive Bacterial Infections/complications

KW - Gram-Positive Cocci/isolation & purification

KW - Humans

KW - Leg Ulcer/complications

KW - Wound Healing/physiology

UR - https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1524-475X.2002.t01-1-10602.x

U2 - 10.1046/j.1524-475X.2002.t01-1-10602.x

DO - 10.1046/j.1524-475X.2002.t01-1-10602.x

M3 - Review article

C2 - 12453137

SN - 1067-1927

VL - 10

SP - 346

EP - 353

JO - Wound Repair and Regeneration

JF - Wound Repair and Regeneration

IS - 6

ER -

Potential role of anaerobic cocci in impaired human wound healing

Abstract

Keywords

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