The incidence of health-care-associated infections has reduced since skin antisepsis was introduced in the 19th century. Despite this, health-care-associated infections, including post-surgical sepsis, continue to cause significant morbidity and mortality. This article reviews the evidence for the use of preoperative skin preparations.
Crosby, C. T., Elliott, T. S. J., Lambert, P. A., & Adams, D. (2009). Preoperative skin preparation: a historical perspective. British Journal of Hospital Medicine, 70(10), 579-582. https://doi.org/10.12968/hmed.2009.70.10.44625