TY - JOUR
T1 - PRINTS and PRINTS-S shed light on protein ancestry
AU - Attwood, T. K.
AU - Blythe, M. J.
AU - Flower, D. R.
AU - Gaulton, A.
AU - Mabey, J. E.
AU - Maudling, N.
AU - McGregor, L.
AU - Mitchell, A. L.
AU - Moulton, G.
AU - Paine, K.
AU - Scordis, P.
PY - 2002/1
Y1 - 2002/1
N2 - The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September 2001 release (version 32.0) includes 1600 fingerprints, encoding ∼10 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here its use as a source of annotation in the InterPro resource, and the use of its relational cousin, PRINTS-S, to model relationships between families, including those beyond the reach of conventional sequence analysis approaches. The database is accessible for BLAST, fingerprint and text searches at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.
AB - The PRINTS database houses a collection of protein fingerprints. These may be used to make family and tentative functional assignments for uncharacterised sequences. The September 2001 release (version 32.0) includes 1600 fingerprints, encoding ∼10 000 motifs, covering a range of globular and membrane proteins, modular polypeptides and so on. In addition to its continued steady growth, we report here its use as a source of annotation in the InterPro resource, and the use of its relational cousin, PRINTS-S, to model relationships between families, including those beyond the reach of conventional sequence analysis approaches. The database is accessible for BLAST, fingerprint and text searches at http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/.
UR - http://nar.oxfordjournals.org/content/30/1/239.full.pdf+html
U2 - 10.1093/nar/30.1.239
DO - 10.1093/nar/30.1.239
M3 - Article
SN - 0305-1048
VL - 30
SP - 239
EP - 241
JO - Nucleic Acids Research
JF - Nucleic Acids Research
IS - 1
ER -