Abstract
Propionibacterium acnes, a common skin organism, is most notably recognized for its role in acne vulgaris. It also causes postoperative and device-related infections and has been associated with a number of other conditions such as sarcoidosis and synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO), although its precise role as a causative agent remains to be determined. Propionibacterium acnes produces a number of virulence factors and is well known for its inflammatory and immunomodulatory properties. Recent publication of the P. acnes genome should provide further insights into the pathogenic capabilities of the organism and potentially lead to the development of new therapies. © 2006 The Society for Applied Microbiology.
| Original language | English |
|---|---|
| Pages (from-to) | 185-188 |
| Number of pages | 4 |
| Journal | Letters in Applied Microbiology |
| Volume | 42 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 2006 |
Keywords
- propionibacterium acnes
- skin organism
- acne vulgaris
- postoperative infection
- device-related infection
- sarcoidosis
- synovitis
- acne
- pustulosis
- hyperostosis
- osteitis
- causative agent
- virulence factor
- genome