Quantum dots as luminescent probes in biological systems

Andrew J. Sutherland

doi:10.1016/S1359-0286(02)00081-5

Quantum dots as luminescent probes in biological systems

Andrew J. Sutherland^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

165 Citations (SciVal)

Abstract

This review describes the recent progress made in exploiting the light emitting properties of quantum dots as luminescent probes for the investigation of non-covalent interactions between two or more biological molecules. The properties of quantum dots and conventional fluorescent probes are compared and methods for attaching quantum dots to biomolecules examined. Such attachment generally involves two stages: quantum dot capping/ coating and subsequent covalent or non-covalent linkage to the biomolecule of interest. Both are addressed. Finally, the use of quantum dots in biological assays is exemplified and the future roles of quantum dots discussed.

Original language	English
Pages (from-to)	365-370
Number of pages	6
Journal	Current Opinion in Solid State and Materials Science
Volume	6
Issue number	4
DOIs	https://doi.org/10.1016/S1359-0286(02)00081-5
Publication status	Published - 1 Aug 2002

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abstract = "This review describes the recent progress made in exploiting the light emitting properties of quantum dots as luminescent probes for the investigation of non-covalent interactions between two or more biological molecules. The properties of quantum dots and conventional fluorescent probes are compared and methods for attaching quantum dots to biomolecules examined. Such attachment generally involves two stages: quantum dot capping/ coating and subsequent covalent or non-covalent linkage to the biomolecule of interest. Both are addressed. Finally, the use of quantum dots in biological assays is exemplified and the future roles of quantum dots discussed.",

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AB - This review describes the recent progress made in exploiting the light emitting properties of quantum dots as luminescent probes for the investigation of non-covalent interactions between two or more biological molecules. The properties of quantum dots and conventional fluorescent probes are compared and methods for attaching quantum dots to biomolecules examined. Such attachment generally involves two stages: quantum dot capping/ coating and subsequent covalent or non-covalent linkage to the biomolecule of interest. Both are addressed. Finally, the use of quantum dots in biological assays is exemplified and the future roles of quantum dots discussed.

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Quantum dots as luminescent probes in biological systems

Abstract

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