Rapid Prototyping of a Low-cost Graphene-based Impedimetric Biosensor

Sinziana Popescu; Carl Dale; Neil Keegan; Biswajit Ghosh; Richard Kaner; John Hedley

doi:10.1016/j.protcy.2017.04.116

Rapid Prototyping of a Low-cost Graphene-based Impedimetric Biosensor

Sinziana Popescu, Carl Dale, Neil Keegan, Biswajit Ghosh, Richard Kaner, John Hedley

College of Health and Life Sciences

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Abstract

This paper presents a preliminary investigation towards rapid prototyping of a low-cost biosensor based on reduced graphene oxide (rGO). The devices are fabricated via a laser scribing process and their functionality is demonstrated by their functionalization and subsequent immobilization of 7% bovine serum albumin (BSA). Non-faradaic electrochemical impedance spectroscopy (EIS) indicated a 33-42% decrease in impedance upon immobilization. An electroless nickel deposition process is demonstrated to enable electrical contacts to the device, with optimized plating conditions (pH, temperature) leading to a rGO-nickel contact resistance of 19 Ω/mm2.

Original language	English
Pages (from-to)	274-276
Journal	Procedia Technology
Volume	27
Early online date	13 Jul 2017
DOIs	https://doi.org/10.1016/j.protcy.2017.04.116
Publication status	Published - 13 Jul 2017

Bibliographical note

Keywords

graphene
reduced graphene oxide
impedimetric biosensor
interdigitated electrode array
electroless nickel deposition

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10.1016/j.protcy.2017.04.116

Rapid prototyping of a low-cost graphene
© 2017 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.
Final published version, 286 KBLicence: CC BY-NC-ND 3.0

http://linkinghub.elsevier.com/retrieve/pii/S2212017317301172

Cite this

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title = "Rapid Prototyping of a Low-cost Graphene-based Impedimetric Biosensor",

abstract = "This paper presents a preliminary investigation towards rapid prototyping of a low-cost biosensor based on reduced graphene oxide (rGO). The devices are fabricated via a laser scribing process and their functionality is demonstrated by their functionalization and subsequent immobilization of 7% bovine serum albumin (BSA). Non-faradaic electrochemical impedance spectroscopy (EIS) indicated a 33-42% decrease in impedance upon immobilization. An electroless nickel deposition process is demonstrated to enable electrical contacts to the device, with optimized plating conditions (pH, temperature) leading to a rGO-nickel contact resistance of 19 Ω/mm2.",

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AU - Dale, Carl

AU - Keegan, Neil

AU - Ghosh, Biswajit

AU - Kaner, Richard

AU - Hedley, John

PY - 2017/7/13

Y1 - 2017/7/13

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AB - This paper presents a preliminary investigation towards rapid prototyping of a low-cost biosensor based on reduced graphene oxide (rGO). The devices are fabricated via a laser scribing process and their functionality is demonstrated by their functionalization and subsequent immobilization of 7% bovine serum albumin (BSA). Non-faradaic electrochemical impedance spectroscopy (EIS) indicated a 33-42% decrease in impedance upon immobilization. An electroless nickel deposition process is demonstrated to enable electrical contacts to the device, with optimized plating conditions (pH, temperature) leading to a rGO-nickel contact resistance of 19 Ω/mm2.

KW - graphene

KW - reduced graphene oxide

KW - impedimetric biosensor

KW - interdigitated electrode array

KW - electroless nickel deposition

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JO - Procedia Technology

JF - Procedia Technology

ER -

Rapid Prototyping of a Low-cost Graphene-based Impedimetric Biosensor

Abstract

Bibliographical note

Keywords

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