Recovery of erythromycin from aqueous solutions with an ionic liquid and high-pressure carbon dioxide

M.S. Manic, M.N. Da Ponte, V. Najdanovic-Visak

Research output: Contribution to journalArticle

Abstract

Recovery of erythromycin from aqueous solutions was studied in two steps: (i) single- and multi-stage extraction of erythromycin from an aqueous solution with a hydrophobic ionic liquid, 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl)imide [BMPyrrol][Tf2N], as a function of pH and feed to solvent volume ratio, and (ii) high-pressure CO2 extraction of erythromycin from the ionic liquid, as a function of pressure, temperature and presence of water. Furthermore, data on the mutual solubilities of the hydrophobic ionic liquid and water, as well as on the solubility of erythromycin in [BMPyrrol][Tf2N], were obtained. The chemical stability of erythromycin in water-free and water saturated ionic liquid was tested.
Original languageEnglish
Pages (from-to)904-911
JournalChemical Engineering Journal
Volume171
Issue number3
DOIs
Publication statusPublished - 15 Jul 2011

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