Regulation of oxygen saturation in retinal blood vessels in response to dynamic exercise

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals.
Methods: Twenty-six healthy participants underwent moderate dynamic exercise (modified Master’s two step exercise). All subjects intraocular pressures (IOP), systolic and diastolic blood pressure (SBP and DBP), retinal vessel calibres and retinal arterial and venous oxygen saturation was measured at baseline, immediately following exercise and 15 minutes post exercise.
Results: Moderate dynamic exercise increased systolic and diastolic blood pressures immediately post exercise (SBP: 116 (+/-13) mmHg to 150 (+/-21) mmHg; p<0.001 and DBP: 69 (+/-10) mmHg to 74 (+/-10); p<0.001) while IOP decreased by an average of 2 mmHg (baseline: 13 (+/-3) mmHg)) immediately post exercise (11 (+/-2) mmHg). Oxygen saturation in retinal arteries remained unchanged (baseline= 93 +/-8%; immediately post exercise=94 +/-9% and 15 minutes post exercise=96 +/-8%; p=0.069) but increased in retinal veins immediately post exercise and did not return to baseline values within 15 minutes post exercise (baseline=54 +/-12%; immediately post exercise=56 +/-15%; 15 minutes post exercise=57 +/-12%; p=0.036). 
Conclusion: There is a mild increase in retinal venous oxygen saturation and a trend towards an increase in arterial saturation in otherwise healthy individuals following dynamic exercise.
LanguageEnglish
Number of pages6
JournalActa Ophthalmologica
Early online date2 Nov 2017
DOIs
Publication statusPublished - 2 Nov 2017

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Retinal Vessels
Exercise
Oxygen
Blood Pressure
Intraocular Pressure
Retinal Artery
Retinal Vein

Bibliographical note

Copyright: 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. This is the peer reviewed version of the following article, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/aos.13576/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.

Funding: Postgraduate scholarship from The College of Optometrists.

Keywords

  • exercise
  • retinal vessel oximetry
  • dual-wavelength
  • autoregulation

Cite this

@article{edd3f21940cf4bb0b8cc9dd6f6d7d2d1,
title = "Regulation of oxygen saturation in retinal blood vessels in response to dynamic exercise",
abstract = "Purpose: To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals.Methods: Twenty-six healthy participants underwent moderate dynamic exercise (modified Master’s two step exercise). All subjects intraocular pressures (IOP), systolic and diastolic blood pressure (SBP and DBP), retinal vessel calibres and retinal arterial and venous oxygen saturation was measured at baseline, immediately following exercise and 15 minutes post exercise.Results: Moderate dynamic exercise increased systolic and diastolic blood pressures immediately post exercise (SBP: 116 (+/-13) mmHg to 150 (+/-21) mmHg; p<0.001 and DBP: 69 (+/-10) mmHg to 74 (+/-10); p<0.001) while IOP decreased by an average of 2 mmHg (baseline: 13 (+/-3) mmHg)) immediately post exercise (11 (+/-2) mmHg). Oxygen saturation in retinal arteries remained unchanged (baseline= 93 +/-8{\%}; immediately post exercise=94 +/-9{\%} and 15 minutes post exercise=96 +/-8{\%}; p=0.069) but increased in retinal veins immediately post exercise and did not return to baseline values within 15 minutes post exercise (baseline=54 +/-12{\%}; immediately post exercise=56 +/-15{\%}; 15 minutes post exercise=57 +/-12{\%}; p=0.036). Conclusion: There is a mild increase in retinal venous oxygen saturation and a trend towards an increase in arterial saturation in otherwise healthy individuals following dynamic exercise.",
keywords = "exercise , retinal vessel oximetry , dual-wavelength , autoregulation",
author = "Rebekka Heitmar and Pravin Vekria and Cubbidge, {Robert P.}",
note = "Copyright: 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. This is the peer reviewed version of the following article, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/aos.13576/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Funding: Postgraduate scholarship from The College of Optometrists.",
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AU - Heitmar, Rebekka

AU - Vekria, Pravin

AU - Cubbidge, Robert P.

N1 - Copyright: 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd. This is the peer reviewed version of the following article, which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/aos.13576/abstract. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Funding: Postgraduate scholarship from The College of Optometrists.

PY - 2017/11/2

Y1 - 2017/11/2

N2 - Purpose: To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals.Methods: Twenty-six healthy participants underwent moderate dynamic exercise (modified Master’s two step exercise). All subjects intraocular pressures (IOP), systolic and diastolic blood pressure (SBP and DBP), retinal vessel calibres and retinal arterial and venous oxygen saturation was measured at baseline, immediately following exercise and 15 minutes post exercise.Results: Moderate dynamic exercise increased systolic and diastolic blood pressures immediately post exercise (SBP: 116 (+/-13) mmHg to 150 (+/-21) mmHg; p<0.001 and DBP: 69 (+/-10) mmHg to 74 (+/-10); p<0.001) while IOP decreased by an average of 2 mmHg (baseline: 13 (+/-3) mmHg)) immediately post exercise (11 (+/-2) mmHg). Oxygen saturation in retinal arteries remained unchanged (baseline= 93 +/-8%; immediately post exercise=94 +/-9% and 15 minutes post exercise=96 +/-8%; p=0.069) but increased in retinal veins immediately post exercise and did not return to baseline values within 15 minutes post exercise (baseline=54 +/-12%; immediately post exercise=56 +/-15%; 15 minutes post exercise=57 +/-12%; p=0.036). Conclusion: There is a mild increase in retinal venous oxygen saturation and a trend towards an increase in arterial saturation in otherwise healthy individuals following dynamic exercise.

AB - Purpose: To evaluate the impact of dynamic exercise on retinal vessel oxygen saturation in healthy individuals.Methods: Twenty-six healthy participants underwent moderate dynamic exercise (modified Master’s two step exercise). All subjects intraocular pressures (IOP), systolic and diastolic blood pressure (SBP and DBP), retinal vessel calibres and retinal arterial and venous oxygen saturation was measured at baseline, immediately following exercise and 15 minutes post exercise.Results: Moderate dynamic exercise increased systolic and diastolic blood pressures immediately post exercise (SBP: 116 (+/-13) mmHg to 150 (+/-21) mmHg; p<0.001 and DBP: 69 (+/-10) mmHg to 74 (+/-10); p<0.001) while IOP decreased by an average of 2 mmHg (baseline: 13 (+/-3) mmHg)) immediately post exercise (11 (+/-2) mmHg). Oxygen saturation in retinal arteries remained unchanged (baseline= 93 +/-8%; immediately post exercise=94 +/-9% and 15 minutes post exercise=96 +/-8%; p=0.069) but increased in retinal veins immediately post exercise and did not return to baseline values within 15 minutes post exercise (baseline=54 +/-12%; immediately post exercise=56 +/-15%; 15 minutes post exercise=57 +/-12%; p=0.036). Conclusion: There is a mild increase in retinal venous oxygen saturation and a trend towards an increase in arterial saturation in otherwise healthy individuals following dynamic exercise.

KW - exercise

KW - retinal vessel oximetry

KW - dual-wavelength

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