Retinal drusen detection using the Nidek F-10 SLO in retro-mode

Jonathan Gibson, Jennifer Acton, Emma Berrow, Paul Galsworthy, Helen King, L. Quant, Karen Whitehouse

Research output: Contribution to conferenceAbstract

Abstract

Presentaton

Purpose:We conducted a small study to assess the novel, retro - mode imaging technique of the NIDEK F-10 scanning laser ophthalmoscope, for detecting and quantifying retinal drusen.

Methods:Fundus photographs of 4 eyes of 2 patients taken in retro-mode on the Nidek F-10 SLO were graded independently by 6,experienced, masked fundus graders for the presence of retinal drusen , and compared to stereo colour fundus photographs taken with a Topcon TRC-50DX camera.

Results:The mean number of retinal drusen detected in retro mode was 142.96+/- 60.8, range 63-265, and on colour fundus photography mean of 66.6+/-32.6, range 26-177. All observers independently detected approximately twice as many drusen on retro-mode than colour fundus photography (p<0.0001, Student’s paired t-test) . The statistical significance of interobserver variation in drusen detection was p=0.07 on colour fundus photography , and p=0.02 on retro mode ( ANOVA) .

Conclusions:The retro-mode of the F-10 camera uses infrared laser and an aperture with a modified central stop, with the aperture deviated laterally from the confocal light path. This forms a pseudo -3D image which is a new means of detecting abnomalites in the deeper retinal layers. Retro-mode imaging of retinal drusen using the F-10 Nidek SLO is a highly sensitive technique for detecting and quantifying retinal drusen , and detected twice as many drusen than colour fundus photography. This small pilot study suggests that this novel type of imaging may have a role in the future detection and analysis of retinal drusen, a field that is likely to become increasingly important in future AMD prevention studies.
Original languageEnglish
Number of pages1
Publication statusPublished - 11 Apr 2009
EventAVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment - Fort Lauderdale, FL, United States
Duration: 3 May 20097 May 2009

Conference

ConferenceAVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment
CountryUnited States
CityFort Lauderdale, FL
Period3/05/097/05/09

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Retinal Drusen
Photography
Color
Lasers
Ophthalmoscopes
Observer Variation
Analysis of Variance
Students
Light

Cite this

Gibson, J., Acton, J., Berrow, E., Galsworthy, P., King, H., Quant, L., & Whitehouse, K. (2009). Retinal drusen detection using the Nidek F-10 SLO in retro-mode. Abstract from AVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment, Fort Lauderdale, FL, United States.
Gibson, Jonathan ; Acton, Jennifer ; Berrow, Emma ; Galsworthy, Paul ; King, Helen ; Quant, L. ; Whitehouse, Karen. / Retinal drusen detection using the Nidek F-10 SLO in retro-mode. Abstract from AVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment, Fort Lauderdale, FL, United States.1 p.
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title = "Retinal drusen detection using the Nidek F-10 SLO in retro-mode",
abstract = "PresentatonPurpose:We conducted a small study to assess the novel, retro - mode imaging technique of the NIDEK F-10 scanning laser ophthalmoscope, for detecting and quantifying retinal drusen.Methods:Fundus photographs of 4 eyes of 2 patients taken in retro-mode on the Nidek F-10 SLO were graded independently by 6,experienced, masked fundus graders for the presence of retinal drusen , and compared to stereo colour fundus photographs taken with a Topcon TRC-50DX camera.Results:The mean number of retinal drusen detected in retro mode was 142.96+/- 60.8, range 63-265, and on colour fundus photography mean of 66.6+/-32.6, range 26-177. All observers independently detected approximately twice as many drusen on retro-mode than colour fundus photography (p<0.0001, Student’s paired t-test) . The statistical significance of interobserver variation in drusen detection was p=0.07 on colour fundus photography , and p=0.02 on retro mode ( ANOVA) .Conclusions:The retro-mode of the F-10 camera uses infrared laser and an aperture with a modified central stop, with the aperture deviated laterally from the confocal light path. This forms a pseudo -3D image which is a new means of detecting abnomalites in the deeper retinal layers. Retro-mode imaging of retinal drusen using the F-10 Nidek SLO is a highly sensitive technique for detecting and quantifying retinal drusen , and detected twice as many drusen than colour fundus photography. This small pilot study suggests that this novel type of imaging may have a role in the future detection and analysis of retinal drusen, a field that is likely to become increasingly important in future AMD prevention studies.",
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year = "2009",
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note = "AVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment ; Conference date: 03-05-2009 Through 07-05-2009",

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Gibson, J, Acton, J, Berrow, E, Galsworthy, P, King, H, Quant, L & Whitehouse, K 2009, 'Retinal drusen detection using the Nidek F-10 SLO in retro-mode', AVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment, Fort Lauderdale, FL, United States, 3/05/09 - 7/05/09.

Retinal drusen detection using the Nidek F-10 SLO in retro-mode. / Gibson, Jonathan; Acton, Jennifer; Berrow, Emma; Galsworthy, Paul; King, Helen; Quant, L.; Whitehouse, Karen.

2009. Abstract from AVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment, Fort Lauderdale, FL, United States.

Research output: Contribution to conferenceAbstract

TY - CONF

T1 - Retinal drusen detection using the Nidek F-10 SLO in retro-mode

AU - Gibson, Jonathan

AU - Acton, Jennifer

AU - Berrow, Emma

AU - Galsworthy, Paul

AU - King, Helen

AU - Quant, L.

AU - Whitehouse, Karen

PY - 2009/4/11

Y1 - 2009/4/11

N2 - PresentatonPurpose:We conducted a small study to assess the novel, retro - mode imaging technique of the NIDEK F-10 scanning laser ophthalmoscope, for detecting and quantifying retinal drusen.Methods:Fundus photographs of 4 eyes of 2 patients taken in retro-mode on the Nidek F-10 SLO were graded independently by 6,experienced, masked fundus graders for the presence of retinal drusen , and compared to stereo colour fundus photographs taken with a Topcon TRC-50DX camera.Results:The mean number of retinal drusen detected in retro mode was 142.96+/- 60.8, range 63-265, and on colour fundus photography mean of 66.6+/-32.6, range 26-177. All observers independently detected approximately twice as many drusen on retro-mode than colour fundus photography (p<0.0001, Student’s paired t-test) . The statistical significance of interobserver variation in drusen detection was p=0.07 on colour fundus photography , and p=0.02 on retro mode ( ANOVA) .Conclusions:The retro-mode of the F-10 camera uses infrared laser and an aperture with a modified central stop, with the aperture deviated laterally from the confocal light path. This forms a pseudo -3D image which is a new means of detecting abnomalites in the deeper retinal layers. Retro-mode imaging of retinal drusen using the F-10 Nidek SLO is a highly sensitive technique for detecting and quantifying retinal drusen , and detected twice as many drusen than colour fundus photography. This small pilot study suggests that this novel type of imaging may have a role in the future detection and analysis of retinal drusen, a field that is likely to become increasingly important in future AMD prevention studies.

AB - PresentatonPurpose:We conducted a small study to assess the novel, retro - mode imaging technique of the NIDEK F-10 scanning laser ophthalmoscope, for detecting and quantifying retinal drusen.Methods:Fundus photographs of 4 eyes of 2 patients taken in retro-mode on the Nidek F-10 SLO were graded independently by 6,experienced, masked fundus graders for the presence of retinal drusen , and compared to stereo colour fundus photographs taken with a Topcon TRC-50DX camera.Results:The mean number of retinal drusen detected in retro mode was 142.96+/- 60.8, range 63-265, and on colour fundus photography mean of 66.6+/-32.6, range 26-177. All observers independently detected approximately twice as many drusen on retro-mode than colour fundus photography (p<0.0001, Student’s paired t-test) . The statistical significance of interobserver variation in drusen detection was p=0.07 on colour fundus photography , and p=0.02 on retro mode ( ANOVA) .Conclusions:The retro-mode of the F-10 camera uses infrared laser and an aperture with a modified central stop, with the aperture deviated laterally from the confocal light path. This forms a pseudo -3D image which is a new means of detecting abnomalites in the deeper retinal layers. Retro-mode imaging of retinal drusen using the F-10 Nidek SLO is a highly sensitive technique for detecting and quantifying retinal drusen , and detected twice as many drusen than colour fundus photography. This small pilot study suggests that this novel type of imaging may have a role in the future detection and analysis of retinal drusen, a field that is likely to become increasingly important in future AMD prevention studies.

UR - http://arvo.abstractsonline.com/Plan/ViewAbstract.aspx?mID=2281&sKey=86bb1a60-7ecf-4cba-bd47-cb96e1d6f3ab&cKey=a7bcc5d5-b0c7-4fb3-ab34-f3321fd44bf9

M3 - Abstract

ER -

Gibson J, Acton J, Berrow E, Galsworthy P, King H, Quant L et al. Retinal drusen detection using the Nidek F-10 SLO in retro-mode. 2009. Abstract from AVRO 2009 Anual meeting: reducing disparities in eye disease ad treatment, Fort Lauderdale, FL, United States.