Ring‐Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post‐Polymerization Modification

Yusheng Chen, James A. Wilson, Shannon R. Petersen, Derek Luong, Sahar Sallam, Jialin Mao, Chrys Wesdemiotis, Matthew L. Becker

Research output: Contribution to journalArticlepeer-review

31 Citations (SciVal)

Abstract

Three functional epoxides were copolymerized with maleic anhydride to yield degradable poly(propylene fumarate) analogues. The polymers were modified post-polymerization and post-printing with either click-type addition reactions or UV deprotection to either attach bioactive species or increase the hydrophilicity. Successful dye attachment, induced wettability, and improved cell spreading show the viability of these analogues in biomaterials applications.
Original languageEnglish
Pages (from-to)12759-12764
JournalAngewandte Chemie International Edition
Volume57
Issue number39
DOIs
Publication statusPublished - 19 Sept 2018

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