SERF: a program for accessible surface area calculations

Darren R. Flower

doi:10.1016/S1093-3263(97)00082-X

SERF: a program for accessible surface area calculations

Darren R. Flower

Astra Charnwood

Research output: Contribution to journal › Article

34 Citations (Scopus)

Abstract

The program SERF has been designed to facilitate the greater use of accessible surface area calculations in the analysis of protein structure, including analysis of surface area changes on binding and complexation. For comparative purposes, the program implements a number of alternative methods for calculating surface areas, including those that approximate residues by single spheres. Algorithmic details, comparative performance, and the software implementation of SERF are discussed

Original language	English
Pages (from-to)	238-244
Number of pages	7
Journal	Journal of Molecular Graphics and Modelling
Volume	15
Issue number	4
DOIs	https://doi.org/10.1016/S1093-3263(97)00082-X
Publication status	Published - Aug 1997

Keywords

molecular surfaces
accessible surface area
macromolecular complexation
sphere packing

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10.1016/S1093-3263(97)00082-X

Cite this

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title = "SERF: a program for accessible surface area calculations",

abstract = "The program SERF has been designed to facilitate the greater use of accessible surface area calculations in the analysis of protein structure, including analysis of surface area changes on binding and complexation. For comparative purposes, the program implements a number of alternative methods for calculating surface areas, including those that approximate residues by single spheres. Algorithmic details, comparative performance, and the software implementation of SERF are discussed",

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year = "1997",

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AU - Flower, Darren R.

PY - 1997/8

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N2 - The program SERF has been designed to facilitate the greater use of accessible surface area calculations in the analysis of protein structure, including analysis of surface area changes on binding and complexation. For comparative purposes, the program implements a number of alternative methods for calculating surface areas, including those that approximate residues by single spheres. Algorithmic details, comparative performance, and the software implementation of SERF are discussed

AB - The program SERF has been designed to facilitate the greater use of accessible surface area calculations in the analysis of protein structure, including analysis of surface area changes on binding and complexation. For comparative purposes, the program implements a number of alternative methods for calculating surface areas, including those that approximate residues by single spheres. Algorithmic details, comparative performance, and the software implementation of SERF are discussed

KW - molecular surfaces

KW - accessible surface area

KW - macromolecular complexation

KW - sphere packing

UR - http://www.sciencedirect.com/science/article/pii/S109332639700082X

U2 - 10.1016/S1093-3263(97)00082-X

DO - 10.1016/S1093-3263(97)00082-X

M3 - Article

SN - 1093-3263

VL - 15

SP - 238

EP - 244

JO - Journal of Molecular Graphics and Modelling

JF - Journal of Molecular Graphics and Modelling

IS - 4

ER -

SERF: a program for accessible surface area calculations

Abstract

Keywords

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