Serial 18F-Fluorodeoxyglucose Positron Emission Tomography to Assess the Efficacy of Infliximab in Steroid Refractory Cardiac Sarcoidosis

Louise E. Crowley; Ellen Jenkins; Akalanka Ranasinghe; Tamara Naneishvili; Mengshi Yuan; Khalid Hussain; Francisco Leyva-Leon; Anjali Crawshaw; William E. Moody

doi:10.1016/j.nuclcard.2025.102265

Serial ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography to Assess the Efficacy of Infliximab in Steroid Refractory Cardiac Sarcoidosis

Louise E. Crowley
, Ellen Jenkins
, Akalanka Ranasinghe
, Tamara Naneishvili
, Mengshi Yuan
, Khalid Hussain
, Francisco Leyva-Leon
, Anjali Crawshaw
, William E. Moody

Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, United Kingdom; Institute for Cardiovascular Sciences, College of Medical and Dental Science, University of Birmingham, Edgbaston, United Kingdom

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Abstract

Graphical abstract (only): Legend: Graphical abstract summarizing the findings of this observational study, which through serial 18F-FDG-PET/CT imaging, supports the use of infliximab in the management of refractory cardiac sarcoidosis. CMA - cardiac metabolic activity, EF - ejection fraction, 18F-FDG-PET/CT - fluorodeoxyglucose-positron emission tomography/computed tomography, LV - left ventricular, MRI - magnetic resonance imaging, SUV - standardized uptake value.

Original language	English
Article number	102265
Journal	Journal of Nuclear Cardiology
Volume	50
Early online date	9 Jun 2025
DOIs	https://doi.org/10.1016/j.nuclcard.2025.102265
Publication status	Published - Aug 2025

Bibliographical note

Copyright © 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society of Nuclear Cardiology. This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).

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Serial 18F-Fluorodeoxyglucose Positron Emission Tomography to Assess the Efficacy of Infliximab in Steroid Refractory Cardiac Sarcoidosis_VoR
Copyright © 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society of Nuclear Cardiology. This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).
Final published version, 654 KBLicence: CC BY 4.0

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Crowley, L. E., Jenkins, E., Ranasinghe, A., Naneishvili, T., Yuan, M., Hussain, K., Leyva-Leon, F., Crawshaw, A., & Moody, W. E. (2025). Serial ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography to Assess the Efficacy of Infliximab in Steroid Refractory Cardiac Sarcoidosis. Journal of Nuclear Cardiology, 50, Article 102265. https://doi.org/10.1016/j.nuclcard.2025.102265

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abstract = "Graphical abstract (only): Legend: Graphical abstract summarizing the findings of this observational study, which through serial 18F-FDG-PET/CT imaging, supports the use of infliximab in the management of refractory cardiac sarcoidosis. CMA - cardiac metabolic activity, EF - ejection fraction, 18F-FDG-PET/CT - fluorodeoxyglucose-positron emission tomography/computed tomography, LV - left ventricular, MRI - magnetic resonance imaging, SUV - standardized uptake value.",

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note = "Copyright {\textcopyright} 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society of Nuclear Cardiology. This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).",

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doi = "10.1016/j.nuclcard.2025.102265",

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AU - Crowley, Louise E.

AU - Jenkins, Ellen

AU - Ranasinghe, Akalanka

AU - Naneishvili, Tamara

AU - Yuan, Mengshi

AU - Hussain, Khalid

AU - Leyva-Leon, Francisco

AU - Crawshaw, Anjali

AU - Moody, William E.

N1 - Copyright © 2025 The Author(s). Published by Elsevier Inc. on behalf of American Society of Nuclear Cardiology. This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/).

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N2 - Graphical abstract (only): Legend: Graphical abstract summarizing the findings of this observational study, which through serial 18F-FDG-PET/CT imaging, supports the use of infliximab in the management of refractory cardiac sarcoidosis. CMA - cardiac metabolic activity, EF - ejection fraction, 18F-FDG-PET/CT - fluorodeoxyglucose-positron emission tomography/computed tomography, LV - left ventricular, MRI - magnetic resonance imaging, SUV - standardized uptake value.

AB - Graphical abstract (only): Legend: Graphical abstract summarizing the findings of this observational study, which through serial 18F-FDG-PET/CT imaging, supports the use of infliximab in the management of refractory cardiac sarcoidosis. CMA - cardiac metabolic activity, EF - ejection fraction, 18F-FDG-PET/CT - fluorodeoxyglucose-positron emission tomography/computed tomography, LV - left ventricular, MRI - magnetic resonance imaging, SUV - standardized uptake value.

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Serial ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography to Assess the Efficacy of Infliximab in Steroid Refractory Cardiac Sarcoidosis

Abstract

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