The local temperature tests demonstrated that the diabetic patients have impaired vasodilation in response to local heating. The tendency for impaired low frequency pulsations of the blood flow associated with endothelial and neurogenic activities in both diabetes groups was observed. Local thermal tests induced variations in perfusion and its spectral characteristics, which were different in the groups under study. In our opinion, the obtained preliminary results can be a basis for further research and provide a deeper understanding of pathological processes that drive microvascular abnormalities caused by diabetes mellitus.
Bibliographical note© 2018, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Funding: RFBR-ra (project 17-41-590560), European Union’s Horizon 2020 Research and Innovation Program grant No 703145, RFBR-ra (project 17-44-590755-ra).
- Non-invasive diagnostics
- Laser Doppler flowmetry
- Blood microcirculation
- Heating test
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Spectral analysis of the blood flow in the foot microvascular bed during thermal testing in patients with diabetes mellitus
Mizeva, I. A. (Creator), Zharkikh, E. V. (Creator), Dremin, V. (Creator), Zherebtsov, E. (Creator), Makovik, I. (Creator), Potapova, E. V. (Creator) & Dunaev, A. V. (Creator), Aston Data Explorer, 21 Jun 2018