Spotlight on...genomics

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Abstract

Genomics has shifted from a research tool to an integral part of obstetric and gynaecological care. The wider ‘-omics’ family—genomics (DNA sequence and variation), transcriptomics (RNA expression), proteomics (protein expression) and metabolomics (metabolic profiles)—all contribute, but genomics currently has the greatest clinical relevance.

Over a decade ago, Horgan and Kenny (TOG 2011;13:189-95)1 predicted that ‘-omics’ would unlock biomarkers, sharpen diagnostics and deliver personalised care. Today, that vision is taking shape: genomics is driving precision medicine, replacing one-size-fits-all models with targeted strategies that improve outcomes for women and their families...
Original languageEnglish
Number of pages3
JournalThe Obstetrician & Gynaecologist
Early online date23 Sept 2025
DOIs
Publication statusE-pub ahead of print - 23 Sept 2025

Bibliographical note

Copyright © 2025 The Author(s). The Obstetrician & Gynaecologist published by John Wiley & Sons Ltd on behalf of Royal College of Obstetricians and Gynaecologists.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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