Stokes-Correlometry Analysis of Biological Tissues with Polycrystalline Structure

Igor Meglinski*, Alexander Ushenko, Anton Sdobnov, Alexander Dubolazov, Marta Grytsiuk, Yuriy Ushenko, Alexander Bykov

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

47 Citations (SciVal)

Abstract

Utilizing Stokes-correlometry analysis a new diagnostic approach has been introduced for quantitative assessment of polarization images of histological sections of optically anisotropic biological tissues with different morphological structures and physiological conditions. The developed approach is based on the quantitative assessment of coordinate and phase distributions of the Stokes vector of scattered light. A combined use of statistic, correlation, and fractal analysis is used for resolving variations in optical anisotropy of biological samples. The proposed combined application of the statistical, correlation, and fractal-based evaluates of spatial distributions of 'single-point' polarization azimuth, ellipticity, and 'two-point' Stokes vector parameters of polarization images of biological tissues histological sections demonstrates a high accuracy ( Ac ≥90%) in monitoring of optical anisotropy variations within biological tissues.

Original languageEnglish
Article number8438957
JournalIEEE Journal of Selected Topics in Quantum Electronics
Volume25
Issue number1
Early online date17 Aug 2018
DOIs
Publication statusPublished - 1 Jan 2019

Funding

Manuscript received April 4, 2018; revised July 24, 2018; accepted July 24, 2018. Date of publication August 17, 2018; date of current version October 12, 2018. This work was supported in part by the Academy of Finland under Grants 311698 and 290596, in part by Tomsk State University Academic D. I. Mendeleev Fund Program, and in part by the National Research Nuclear University MEPhI’s Academic Excellence Project under Contract 02.a03.21.0005. (Corresponding author: Igor Meglinski.) A. Ushenko, A. Dubolazov, M. Gritsuk, and Y. Ushenko are with the Chernivtsi National University, Chernivtsi 58012, Ukraine (e-mail:,ushenko@ mail.ru; [email protected]; [email protected]; [email protected]).

Keywords

  • ellipsometry and polarimetry
  • Polarimetric imaging
  • polarization
  • Stokes-correlometry

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