Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter contains sections titled:
Introduction
Structure and Regulation
Physiologic Functions of TG2
Disruption of TG2 Functions in Pathologic Conditions
Perspectives for Pharmacologic Interventions
Concluding Comments
Acknowledgements
References
LanguageEnglish
Title of host publicationAdvances in enzymology
Subtitle of host publicationand related areas of molecular biology
EditorsEric J. Toone
Place of PublicationHoboken, NJ (US)
PublisherWiley
Pages1-46
Number of pages46
Volume78
ISBN (Electronic)978-1-118-10577-1
ISBN (Print)978-1-118-01428-8, 1-118-01428-6
DOIs
Publication statusPublished - 16 Dec 2011

Fingerprint

transglutaminase 2

Keywords

  • animals
  • catalysis
  • disease
  • GTP-binding proteins
  • enzymologic gene expression regulation
  • humans
  • biological models
  • molecular models
  • molecular targeted therapy
  • structure-activity relationship
  • tissue distribution
  • transglutaminases

Cite this

Bergamini, C. M., Collighan, R. J., Wang, Z., & Griffin, M. (2011). Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. In E. J. Toone (Ed.), Advances in enzymology: and related areas of molecular biology (Vol. 78, pp. 1-46). Hoboken, NJ (US): Wiley. https://doi.org/10.1002/9781118105771.ch1
Bergamini, Carlo M. ; Collighan, Russell J ; Wang, Zhuo ; Griffin, Martin. / Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. Advances in enzymology: and related areas of molecular biology. editor / Eric J. Toone. Vol. 78 Hoboken, NJ (US) : Wiley, 2011. pp. 1-46
@inbook{bfdf070d82e04057afea1c5f836ea8e2,
title = "Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles",
abstract = "This chapter contains sections titled: IntroductionStructure and RegulationPhysiologic Functions of TG2Disruption of TG2 Functions in Pathologic ConditionsPerspectives for Pharmacologic InterventionsConcluding CommentsAcknowledgementsReferences",
keywords = "animals, catalysis, disease, GTP-binding proteins, enzymologic gene expression regulation, humans, biological models, molecular models, molecular targeted therapy, structure-activity relationship, tissue distribution, transglutaminases",
author = "Bergamini, {Carlo M.} and Collighan, {Russell J} and Zhuo Wang and Martin Griffin",
year = "2011",
month = "12",
day = "16",
doi = "10.1002/9781118105771.ch1",
language = "English",
isbn = "978-1-118-01428-8",
volume = "78",
pages = "1--46",
editor = "Toone, {Eric J.}",
booktitle = "Advances in enzymology",
publisher = "Wiley",

}

Bergamini, CM, Collighan, RJ, Wang, Z & Griffin, M 2011, Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. in EJ Toone (ed.), Advances in enzymology: and related areas of molecular biology. vol. 78, Wiley, Hoboken, NJ (US), pp. 1-46. https://doi.org/10.1002/9781118105771.ch1

Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. / Bergamini, Carlo M.; Collighan, Russell J; Wang, Zhuo; Griffin, Martin.

Advances in enzymology: and related areas of molecular biology. ed. / Eric J. Toone. Vol. 78 Hoboken, NJ (US) : Wiley, 2011. p. 1-46.

Research output: Chapter in Book/Report/Conference proceedingChapter

TY - CHAP

T1 - Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

AU - Bergamini, Carlo M.

AU - Collighan, Russell J

AU - Wang, Zhuo

AU - Griffin, Martin

PY - 2011/12/16

Y1 - 2011/12/16

N2 - This chapter contains sections titled: IntroductionStructure and RegulationPhysiologic Functions of TG2Disruption of TG2 Functions in Pathologic ConditionsPerspectives for Pharmacologic InterventionsConcluding CommentsAcknowledgementsReferences

AB - This chapter contains sections titled: IntroductionStructure and RegulationPhysiologic Functions of TG2Disruption of TG2 Functions in Pathologic ConditionsPerspectives for Pharmacologic InterventionsConcluding CommentsAcknowledgementsReferences

KW - animals

KW - catalysis

KW - disease

KW - GTP-binding proteins

KW - enzymologic gene expression regulation

KW - humans

KW - biological models

KW - molecular models

KW - molecular targeted therapy

KW - structure-activity relationship

KW - tissue distribution

KW - transglutaminases

UR - http://www.scopus.com/inward/record.url?scp=84863011664&partnerID=8YFLogxK

UR - http://onlinelibrary.wiley.com/doi/10.1002/9781118105771.ch1/summary

U2 - 10.1002/9781118105771.ch1

DO - 10.1002/9781118105771.ch1

M3 - Chapter

SN - 978-1-118-01428-8

SN - 1-118-01428-6

VL - 78

SP - 1

EP - 46

BT - Advances in enzymology

A2 - Toone, Eric J.

PB - Wiley

CY - Hoboken, NJ (US)

ER -

Bergamini CM, Collighan RJ, Wang Z, Griffin M. Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. In Toone EJ, editor, Advances in enzymology: and related areas of molecular biology. Vol. 78. Hoboken, NJ (US): Wiley. 2011. p. 1-46 https://doi.org/10.1002/9781118105771.ch1