Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter contains sections titled:
Introduction
Structure and Regulation
Physiologic Functions of TG2
Disruption of TG2 Functions in Pathologic Conditions
Perspectives for Pharmacologic Interventions
Concluding Comments
Acknowledgements
References
Original languageEnglish
Title of host publicationAdvances in enzymology
Subtitle of host publicationand related areas of molecular biology
EditorsEric J. Toone
Place of PublicationHoboken, NJ (US)
PublisherWiley
Pages1-46
Number of pages46
Volume78
ISBN (Electronic)978-1-118-10577-1
ISBN (Print)978-1-118-01428-8, 1-118-01428-6
DOIs
Publication statusPublished - 16 Dec 2011

Keywords

  • animals
  • catalysis
  • disease
  • GTP-binding proteins
  • enzymologic gene expression regulation
  • humans
  • biological models
  • molecular models
  • molecular targeted therapy
  • structure-activity relationship
  • tissue distribution
  • transglutaminases

Fingerprint Dive into the research topics of 'Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles'. Together they form a unique fingerprint.

  • Cite this

    Bergamini, C. M., Collighan, R. J., Wang, Z., & Griffin, M. (2011). Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. In E. J. Toone (Ed.), Advances in enzymology: and related areas of molecular biology (Vol. 78, pp. 1-46). Wiley. https://doi.org/10.1002/9781118105771.ch1