Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Carlo M. Bergamini; Russell J Collighan; Zhuo Wang; Martin Griffin

doi:10.1002/9781118105771.ch1

Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Duke University

Research output: Chapter in Book/Published conference output › Chapter

22 Citations (Scopus)

Abstract

This chapter contains sections titled:
Introduction
Structure and Regulation
Physiologic Functions of TG2
Disruption of TG2 Functions in Pathologic Conditions
Perspectives for Pharmacologic Interventions
Concluding Comments
Acknowledgements
References

Original language	English
Title of host publication	Advances in enzymology
Subtitle of host publication	and related areas of molecular biology
Editors	Eric J. Toone
Place of Publication	Hoboken, NJ (US)
Publisher	Wiley
Pages	1-46
Number of pages	46
Volume	78
ISBN (Electronic)	978-1-118-10577-1
ISBN (Print)	978-1-118-01428-8, 1-118-01428-6
DOIs	https://doi.org/10.1002/9781118105771.ch1
Publication status	Published - 16 Dec 2011

Keywords

animals
catalysis
disease
GTP-binding proteins
enzymologic gene expression regulation
humans
biological models
molecular models
molecular targeted therapy
structure-activity relationship
tissue distribution
transglutaminases

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10.1002/9781118105771.ch1

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title = "Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles",

abstract = "This chapter contains sections titled: Introduction Structure and Regulation Physiologic Functions of TG2 Disruption of TG2 Functions in Pathologic Conditions Perspectives for Pharmacologic Interventions Concluding Comments Acknowledgements References",

keywords = "animals, catalysis, disease, GTP-binding proteins, enzymologic gene expression regulation, humans, biological models, molecular models, molecular targeted therapy, structure-activity relationship, tissue distribution, transglutaminases",

author = "Bergamini, \{Carlo M.\} and Collighan, \{Russell J\} and Zhuo Wang and Martin Griffin",

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Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles. / Bergamini, Carlo M.; Collighan, Russell J ; Wang, Zhuo et al.
Advances in enzymology: and related areas of molecular biology. ed. / Eric J. Toone. Vol. 78 Hoboken, NJ (US): Wiley, 2011. p. 1-46.

Research output: Chapter in Book/Published conference output › Chapter

TY - CHAP

T1 - Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

AU - Bergamini, Carlo M.

AU - Collighan, Russell J

AU - Wang, Zhuo

AU - Griffin, Martin

PY - 2011/12/16

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N2 - This chapter contains sections titled: Introduction Structure and Regulation Physiologic Functions of TG2 Disruption of TG2 Functions in Pathologic Conditions Perspectives for Pharmacologic Interventions Concluding Comments Acknowledgements References

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KW - animals

KW - catalysis

KW - disease

KW - GTP-binding proteins

KW - enzymologic gene expression regulation

KW - humans

KW - biological models

KW - molecular models

KW - molecular targeted therapy

KW - structure-activity relationship

KW - tissue distribution

KW - transglutaminases

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DO - 10.1002/9781118105771.ch1

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SN - 978-1-118-01428-8

SN - 1-118-01428-6

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BT - Advances in enzymology

A2 - Toone, Eric J.

PB - Wiley

CY - Hoboken, NJ (US)

ER -

Structure and regulation of type 2 transglutaminase in relation to its physiological functions and pathological roles

Abstract

Keywords

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