TY - JOUR
T1 - Synthesis, processing and tensile testing of a poly(l -lactide-co-caprolactone) monofilament fiber for use as an absorbable surgical suture
AU - Ruengdechawiwat, Sujitra
AU - Molloy, Robert
AU - Siripitayananon, Jintana
AU - Somsunan, Runglawan
AU - Topham, Paul D.
AU - Tighe, Brian J.
PY - 2015/8/25
Y1 - 2015/8/25
N2 - A poly(l-lactide-co-caprolactone), P(LL-co-CL), 75:25 mol % copolymer was synthesized via the bulk ring-opening copolymerization of l-lactide (LL) and ε-caprolactone (CL) at 130 °C for 48 hrs. The P(LL-co-CL) copolymer obtained was characterized in terms of its molecular weight (GPC), copolymer composition (1H-NMR), monomer sequencing (13C-NMR) and thermal properties (DSC, TGA). For processing, the P(LL-co-CL) was melt spun into a monofilament fiber with fast cooling and minimal draw in order to produce an as-spun fiber that was largely amorphous and unoriented. This enabled the required oriented semi-crystalline morphology to be gradually built into the as-spun fiber in a series of controlled off-line annealing and hot-drawing steps. The final fiber, which combined sufficient tensile strength with flexibility for use as a suture material, exhibited a stress and strain at break of 344 MPa and 70%, respectively.
AB - A poly(l-lactide-co-caprolactone), P(LL-co-CL), 75:25 mol % copolymer was synthesized via the bulk ring-opening copolymerization of l-lactide (LL) and ε-caprolactone (CL) at 130 °C for 48 hrs. The P(LL-co-CL) copolymer obtained was characterized in terms of its molecular weight (GPC), copolymer composition (1H-NMR), monomer sequencing (13C-NMR) and thermal properties (DSC, TGA). For processing, the P(LL-co-CL) was melt spun into a monofilament fiber with fast cooling and minimal draw in order to produce an as-spun fiber that was largely amorphous and unoriented. This enabled the required oriented semi-crystalline morphology to be gradually built into the as-spun fiber in a series of controlled off-line annealing and hot-drawing steps. The final fiber, which combined sufficient tensile strength with flexibility for use as a suture material, exhibited a stress and strain at break of 344 MPa and 70%, respectively.
KW - absorbable monofilament suture
KW - fibers
KW - l -Lactide
KW - melt spinning
KW - ring-opening polymerization
KW - ε-caprolactone
UR - http://www.scopus.com/inward/record.url?scp=84940121926&partnerID=8YFLogxK
UR - https://onlinelibrary.wiley.com/doi/full/10.1002/masy.201400077
U2 - 10.1002/masy.201400077
DO - 10.1002/masy.201400077
M3 - Article
AN - SCOPUS:84940121926
SN - 1022-1360
VL - 354
SP - 347
EP - 353
JO - Macromolecular Symposia
JF - Macromolecular Symposia
IS - 1
ER -