Synthetic ceramides inhibit CD36 expression in U937 cells through a reduction in cytosolic peroxide

Keyphrases

• Atherosclerotic Plaque 9%
• CD36 Expression 100%
• Cellular Compartments 9%
• Cellular Glutathione 9%
• Cellular Response 9%
• Ceramide 100%
• Cluster of Differentiation 36 (CD36) 18%
• Dose Effect 9%
• Environmental Agents 9%
• Flow Cytometry 9%
• Gene Expression 9%
• Glutathione 9%
• Glutathione Peroxidase (GSH-Px) 9%
• Growth Arrest 9%
• Intracellular Redox State 9%
• Intracellular Signal Transduction 9%
• LDL Aggregation 9%
• Macrophages 18%
• Mitochondrial Reactive Oxygen Species (mtROS) 9%
• MRNA Level 9%
• N-acetylcysteine 9%
• Oxidized Low-density Lipoprotein (ox-LDL) 9%
• Oxygen Redox 9%
• Peroxide 100%
• Pharmacological Agents 9%
• Protein Level 9%
• Quantitative PCR 9%
• Reactive Oxygen Species 27%
• Reactive Oxygen Species Production 9%
• Reactive Oxygen Species Responsive 9%
• Reciprocal Regulation 9%
• Redox 9%
• Redox-sensitive 18%
• Scavenger Receptor CD36 9%
• Sensitivity Genes 18%
• Short-chain Ceramides 9%
• Sphingolipids 9%
• Sphingomyelin 9%
• Stress-induced 9%
• U937 Cells 100%
• U937 Macrophages 9%
• U937 Monocytes 18%

Neuroscience

• Acetylcysteine 8%
• CD36 100%
• Ceramide 100%
• Flow Cytometry 8%
• Gene Expression 8%
• Glutathione 16%
• Glutathione Peroxidase 8%
• Growth Disorder 8%
• In Vivo 8%
• Macrophage 25%
• Messenger RNA 8%
• Oxidized Low Density Lipoprotein 8%
• Peroxidase 8%
• Reactive Oxygen Species 41%
• Scavenger Receptor 8%
• Signal Transduction 8%
• Sphingolipid 8%
• Sphingomyelin 8%

Biochemistry, Genetics and Molecular Biology

• Acetylcysteine 8%
• CD36 100%
• Ceramide 100%
• Flow Cytometry 8%
• Gene Expression 8%
• Glutathione 16%
• Glutathione Peroxidase 8%
• Macrophage 25%
• Messenger RNA 8%
• Peroxidase 8%
• Reverse Transcription Polymerase Chain Reaction 8%
• Scavenger Receptor 8%
• Signal Transduction 8%
• Sphingolipid 8%
• Sphingomyelin 8%