Technical recommendations for analyzing oxylipins by liquid chromatography–mass spectrometry

Nils Helge Schebb, Nadja Kampschulte, Gerhard Hagn, Kathrin Plitzko, + 90 authors inc., Corinne Spickett, Irundika Dias, Ivana Milic, et al (over 30 authors)

Research output: Contribution to journalArticlepeer-review

Abstract

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography–mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.
Original languageEnglish
Article numbereadw1245
JournalScience Signaling
Volume18
Issue number887
Early online date20 May 2025
DOIs
Publication statusPublished - 20 May 2025

Bibliographical note

Copyright © 2025 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. This is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science Signaling, Volume 18 (2025). DOI: https://doi.org/10.1126/scisignal.adw1245

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