Terahertz time-domain spectroscopy for non-invasive assessment of water content in biological samples

Mariia Borovkova*, Mikhail Khodzitsky, Petr Demchenko, Olga Cherkasova, Alexey Popov, Igor Meglinski

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We apply terahertz time-domain spectroscopy for the quantitative non-invasive assessment of the water content in biological samples, such as Carpinus caroliniana tree leaves and pork muscles. The developed experimental terahertz time-domain spectroscopy system operates both in transmission and reflection modes. The Landau-Looyenga-Lifshitz-based model is used for the calculation of the water concentration within the samples. The results of the water concentration measurements are compared with the results of the gravimetric measurements. The obtained results show that the water content in biological samples can be measured non-invasively, with a high accuracy, utilizing terahertz waves in transmission and reflection modes.

Original languageEnglish
Article number#309306
Pages (from-to)2266-2276
Number of pages11
JournalBiomedical Optics Express
Volume9
Issue number5
Early online date20 Apr 2018
DOIs
Publication statusPublished - 1 May 2018

Bibliographical note

© 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Keywords

  • Medical and biological imaging
  • Optical diagnostics for medicine
  • Spectroscopy, terahertz
  • Terahertz imaging
  • Tissue

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