The anti-psychotic drug Pimozide is a Novel chemotherapeutic for Breast Cancer

Keyphrases

• Breast Cancer 100%
• Antipsychotics 100%
• Pimozide 100%
• Breast Cancer Cells 33%
• MDA-MB-231 25%
• In Vivo Antitumor Activity 16%
• Inhibitory Effect 8%
• DNA Double-strand Breaks 8%
• In Cancer 8%
• Apoptosis 8%
• Protein Level 8%
• MRNA Level 8%
• Cell Proliferation 8%
• Cell Growth 8%
• Cell Migration 8%
• Stromal Cells 8%
• Cell Cycle Arrest 8%
• Angiogenesis 8%
• Breast Cell Lines 8%
• Molecular Pathways 8%
• Paracrine 8%
• Inhibit Tumor 8%
• Myofibroblast 8%
• Cancer Cells 8%
• Cancer Therapy 8%
• Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) 8%
• AKT Pathway 8%
• α-smooth muscle Actin (α-SMA) 8%
• Tumor Development 8%
• Epithelial-mesenchymal Transition 8%
• Mesenchymal Cells 8%
• Lung Metastasis 8%
• MCF10A 8%
• Xenograft Animal Model 8%
• Cell Lung Cancer 8%
• A549 Lung Cancer Cells 8%
• Ran GTPase 8%
• Lung Cancer Cells 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Breast Cancer 100%
• Antipsychotic 100%
• Pimozide 100%
• Malignant Neoplasm 16%
• Antitumor Activity 16%
• Lung Cancer 16%
• Neoplasm 8%
• Messenger RNA 8%
• Double Stranded DNA 8%
• Vasculotropin Receptor 2 8%
• Smooth Muscle Actin 8%
• Lung Metastasis 8%
• Guanosine Triphosphatase 8%
• Diphenylbutylpiperidine 8%