The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Y. Li, E.O. McKenna, W. Parkes, A.R. Pitt, A.J. Walton

Research output: Contribution to journalArticle

Abstract

A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straightforward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.

LanguageEnglish
Article number073703
Number of pages3
JournalApplied Physics Letters
Volume99
Issue number7
DOIs
Publication statusPublished - 15 Aug 2011

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aqueous solutions
proteins
fabrication
thin films

Bibliographical note

Copyright © 2011 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Appl. Phys. Lett. 99, 073703 (2011); and may be found at https://doi.org/10.1063/1.3626037

Cite this

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The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays. / Li, Y.; McKenna, E.O.; Parkes, W.; Pitt, A.R.; Walton, A.J.

In: Applied Physics Letters, Vol. 99, No. 7, 073703, 15.08.2011.

Research output: Contribution to journalArticle

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